A high-performance method of deep learning for prostate MR-only radiotherapy planning using an optimized Pix2Pix architecture.

Journal: Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Published Date: Oct 19, 2022

Abstract

PURPOSE: The first aim was to generate and compare synthetic-CT (sCT) images using a conditional generative adversarial network (cGAN) method (Pix2Pix) for MRI-only prostate radiotherapy planning by testing several generators, loss functions, and hyper-parameters. The second aim was to compare the optimized Pix2Pix model with five other architectures (bulk-density, atlas-based, patch-based, U-Net, and GAN).

Authors

  • S Tahri
    Univ. Rennes 1, CLCC Eugène Marquis, INSERM, LTSI - UMR 1099, F-35000 Rennes, France.
  • A Barateau
    Univ. Rennes 1, CLCC Eugène Marquis, INSERM, LTSI - UMR 1099, F-35000 Rennes, France.
  • C Cadin
    Univ. Rennes 1, CLCC Eugène Marquis, INSERM, LTSI - UMR 1099, F-35000 Rennes, France.
  • H Chourak
    Univ. Rennes 1, CLCC Eugène Marquis, INSERM, LTSI - UMR 1099, F-35000 Rennes, France; CSIRO Australian e-Health Research Centre, Herston, Queensland, Australia.
  • S Ribault
    Univ. Rennes 1, CLCC Eugène Marquis, INSERM, LTSI - UMR 1099, F-35000 Rennes, France.
  • F Nozahic
    Univ. Rennes 1, CLCC Eugène Marquis, INSERM, LTSI - UMR 1099, F-35000 Rennes, France.
  • O Acosta
    Univ. Rennes 1, CLCC Eugène Marquis, INSERM, LTSI - UMR 1099, F-35000 Rennes, France.
  • J A Dowling
    CSIRO Australian e-Health Research Centre, Herston, Queensland, Australia.
  • P B Greer
    School of Mathematical and Physical Sciences, University of Newcastle, Newcastle, Australia; Department of Radiation Oncology, Calvary Mater, Newcastle, Australia.
  • A Largent
    Developing Brain Institute, Department of Diagnostic Imaging and Radiology, Children's National Hospital, Washington, DC, USA.
  • C Lafond
    Univ. Rennes 1, CLCC Eugène Marquis, INSERM, LTSI - UMR 1099, F-35000 Rennes, France.
  • R De Crevoisier
    Univ. Rennes 1, CLCC Eugène Marquis, INSERM, LTSI - UMR 1099, F-35000 Rennes, France.
  • J C Nunes
    Univ. Rennes 1, CLCC Eugène Marquis, INSERM, LTSI - UMR 1099, F-35000 Rennes, France.

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