Deep learning assisted contrast-enhanced CT-based diagnosis of cervical lymph node metastasis of oral cancer: a retrospective study of 1466 cases.

Journal: European radiology
Published Date:

Abstract

OBJECTIVES: Lymph node (LN) metastasis is a common cause of recurrence in oral cancer; however, the accuracy of distinguishing positive and negative LNs is not ideal. Here, we aimed to develop a deep learning model that can identify, locate, and distinguish LNs in contrast-enhanced CT (CECT) images with a higher accuracy.

Authors

  • Xiaoshuai Xu
    The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan, China.
  • Linlin Xi
    School of Computer Science, Wuhan University, 299 Bayi Road, Wuhan, 430072, Hubei, China.
  • Lili Wei
    Shandong Institute for Food and Drug Control, Ji'nan 250101, China.
  • Luping Wu
    The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan, China.
  • Yuming Xu
  • Bailve Liu
    School of Computer Science, Wuhan University, 299 Bayi Road, Wuhan, 430072, Hubei, China.
  • Bo Li
    Electric Power Research Institute, Yunnan Power Grid Co., Ltd., Kunming, Yunnan, China.
  • Ke Liu
    State Key Laboratory of Stress Cell Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian 361102, P.R. China.
  • Gaigai Hou
    The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan, China.
  • Hao Lin
    Yangtze Delta Region Institute (Huzhou), University of Electronic Science and Technology of China, Huzhou, Zhejiang, China.
  • Zhe Shao
    The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan, China. shaozhe@whu.edu.cn.
  • Kehua Su
    School of Computer Science, Wuhan University, 299 Bayi Road, Wuhan, 430072, Hubei, China. skh@whu.edu.cn.
  • Zhengjun Shang
    The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan, China. shangzhengjun@whu.edu.cn.