Sporulated Bacillus as alternative treatment for diarrhea of hospitalized adult patients under enteral nutrition: A pilot randomized controlled study.

Journal: Clinical nutrition ESPEN
PMID: 29415828

Abstract

BACKGROUND & AIMS: Among hospitalized patients receiving enteral nutrition (EN), malnutrition and antibiotic use are some of the most common causes of diarrhea. Prebiotics and probiotics agents have been used for treatment of diarrhea in such patients. The aim of this study was to assess the efficacy of a sporulated Bacillus strain (Bacillus cereus A 05), compared to a control group using a prebiotic (soluble fiber), in reducing diarrhea in patients receiving EN and antibiotic therapy.

Authors

  • Gustavo Gomes de Castro Soares
    Hospital Pilar, Avenida Hugo Simas, 322, Bom Retiro, Curitiba, PR, 80.520-250, Brazil. Electronic address: gustavogcs@terra.com.br.
  • Carlos Hespanha Marinho
    Hospital Pilar, Avenida Hugo Simas, 322, Bom Retiro, Curitiba, PR, 80.520-250, Brazil.
  • Regiane Pitol
    Hospital Pilar, Avenida Hugo Simas, 322, Bom Retiro, Curitiba, PR, 80.520-250, Brazil.
  • Camila Andretta
    Hospital Pilar, Avenida Hugo Simas, 322, Bom Retiro, Curitiba, PR, 80.520-250, Brazil.
  • Edinaldo Oliveira
    Hospital Pilar, Avenida Hugo Simas, 322, Bom Retiro, Curitiba, PR, 80.520-250, Brazil.
  • Cristina Martins
    Instituto Cristina Martins de Educação em Saúde, Avenida Hugo Simas, 322, Bom Retiro, Curitiba, PR, 80.520-250, Brazil. Electronic address: cristina@cristinamartins.org.
  • Miguel Carlos Riella
    Pró-renal Brazil Foundation, Center for Health and Biological Sciences, Pontifícia Universidade Católica do Paraná (pucpr), Avenida Hugo Simas, 322, Bom Retiro, Curitiba, PR, 80.520-250, Brazil. Electronic address: mcriella@pro-renal.org.br.

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