Evaluation of real-time tumor contour prediction using LSTM networks for MR-guided radiotherapy.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Published Date: Feb 21, 2023

Abstract

BACKGROUND AND PURPOSE: Magnetic resonance imaging guided radiotherapy (MRgRT) with deformable multileaf collimator (MLC) tracking would allow to tackle both rigid displacement and tumor deformation without prolonging treatment. However, the system latency must be accounted for by predicting future tumor contours in real-time. We compared the performance of three artificial intelligence (AI) algorithms based on long short-term memory (LSTM) modules for the prediction of 2D-contours 500ms into the future.

Authors

  • Elia Lombardo
    Department of Radiation Oncology, University Hospital, LMU Munich, Munich, 81377, Germany.
  • Moritz Rabe
    Department of Radiation Oncology, University Hospital, LMU Munich, Munich 81377, Germany.
  • Yuqing Xiong
    Department of Radiation Oncology, University Hospital, LMU Munich, Munich 81377, Germany.
  • Lukas Nierer
    Department of Radiation Oncology, University Hospital, LMU Munich, Munich, Germany.
  • Davide Cusumano
    Polo Scienze Oncologiche ed Ematologiche, Fondazione Policlinico Universitario Agostino Gemelli, Largo A. Gemelli, 8, 00168 Rome, Italy.
  • Lorenzo Placidi
    Radiation Oncology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Luca Boldrini
    Radiation Oncology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
  • Stefanie Corradini
    Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
  • Maximilian Niyazi
    Department of Radiation Oncology, University Hospital Tübingen, Tübingen, Germany.
  • Michael Reiner
    Department of Radiation Oncology, University Hospital, LMU Munich, Munich 81377, Germany.
  • Claus Belka
    Department of Radiation Oncology, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
  • Christopher Kurz
    Department of Medical Physics, Faculty of Physics, Ludwig-Maximilians-Universität München (LMU Munich), Garching bei München, 85748, Germany.
  • Marco Riboldi
    Department of Medical Physics, Ludwig-Maximilians-Universität München, Germany.
  • Guillaume Landry
    Department of Medical Physics, Faculty of Physics, Ludwig-Maximilians-Universität München (LMU Munich), Garching bei München, 85748, Germany.

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