Do perioperative blood transfusions impact oncological outcomes of robot-assisted radical cystectomy with intracorporeal urinary diversion? Results from a large multi-institutional registry.

Journal: Minerva urology and nephrology
PMID:

Abstract

BACKGROUND: Blood transfusions (BT) have been associated with adverse oncologic outcomes in multiple malignancies including open radical cystectomy (ORC) for urothelial carcinoma of the bladder (UCB). Robot-assisted radical cystectomy (RARC) with intracorporeal urinary diversion (ICUD) delivers similar oncologic outcomes compared to ORC, yet with lower blood loss and reduced transfusions. However, the impact of BT after robotic cystectomy is still unknown.

Authors

  • Julien Sarkis
    Department of Urology, Hôtel-Dieu de France Hospital, Beirut, Lebanon.
  • Romain Diamand
    Department of Urology, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
  • Fouad Aoun
    Department of Urology, Hotel Dieu de France, Beirut, Lebanon.
  • Gregoire Assenmacher
    Department of Urology, Cliniques de l'Europe-Saint Elisabeth, Brussels, Belgium.
  • Christophe Assenmacher
    Department of Urology, Cliniques de l'Europe-Saint Elisabeth, Brussels, Belgium.
  • Grégory Verhoest
    Department of Urology, Rennes University Hospital, 2, rue Henri Le Guilloux, 35033, Rennes Cedex, France.
  • Serge Holz
    Department of Urology, CHU Ambroise Paré, Mons, Belgium.
  • Michel Naudin
    Department of Urology, CHU Ambroise Paré, Mons, Belgium.
  • Guillaume Ploussard
    Department of Urology, La Croix du Sud Hospital, Quint Fonsegrives, France.
  • Andrea Mari
  • Andrea Minervini
    Department of Urology, Careggi Hospital, University of Florence, Florence, Italy.
  • Andrea Tay
    Department of Urology, Saint Georges Hospital, London, United Kingdom.
  • Rami Issa
    Department of Urology, Saint Georges Hospital, London, United Kingdom.
  • Mathieu Roumiguié
    Department of Urology, University of Toulouse, Toulouse, France.
  • Anne S Bajeot
    Department of Urology, Andrology and Renal Transplantation, CHU Rangueil, Paul-Sabatier University, Toulouse Cedex, France.
  • Giuseppe Simone
    Department of Urology, Regina Elena National Cancer Institute, Rome, Italy.
  • Umberto Anceschi
    Department of Urology, Regina Elena National Cancer Institute, Rome, Italy. Electronic address: umberto.anceschi@gmail.com.
  • Paolo Umari
    Division of Surgery and Interventional Sciences, University College London, London, UK.
  • Ashwin Sridhar
    Department of Urology and Division of Surgery and Interventional Science, University College London Hospital, London, UK.
  • John Kelly
    Department of Urology, University College London Hospital, London, UK.
  • Kees Hendricksen
    Department of Urology, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
  • Sarah Einerhand
    Department of Urology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Laura S Mertens
    Department of Urology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Rafael Sanchez-Salas
    Department of Urology, Institut Mutualiste Montsouris, Paris, France.
  • Anna Colomer
    Department of Urology, Institut Mutualiste Montsouris, Paris, France.
  • Thierry Quackels
    Department of Urology, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium.
  • Alexandre Peltier
    Department of Urology, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.
  • Francesco Montorsi
    Unit of Urology/Division of Oncology, Gianfranco Soldera Prostate Cancer Lab, URI, IRCCS San Raffaele Scientific Institute, Via Olgettina 58, 20132, Milan, Italy.
  • Alberto Briganti
    Unit of Urology/Division of Oncology, Gianfranco Soldera Prostate Cancer Lab, URI, IRCCS San Raffaele Scientific Institute, Via Olgettina 58, 20132, Milan, Italy.
  • Benjamin Pradere
    Department of Urology, University of Tours, Tours, France.
  • Marco Moschini
    Division of Oncology/Unit of Urology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.
  • Thierry Roumeguère
    Department of Urology, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium.
  • Simone Albisinni
    Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.