Long-term epilepsy outcome dynamics revealed by natural language processing of clinic notes.

Journal: Epilepsia
Published Date: May 10, 2023

Abstract

OBJECTIVE: Electronic medical records allow for retrospective clinical research with large patient cohorts. However, epilepsy outcomes are often contained in free text notes that are difficult to mine. We recently developed and validated novel natural language processing (NLP) algorithms to automatically extract key epilepsy outcome measures from clinic notes. In this study, we assessed the feasibility of extracting these measures to study the natural history of epilepsy at our center.

Authors

  • Kevin Xie
    Department of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Ryan S Gallagher
    Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Russell T Shinohara
    Artificial Intelligence in Biomedical Imaging Laboratory (AIBIL), Center for and Data Science for Integrated Diagnostics (AID), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Sharon X Xie
    Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Chloe E Hill
    Department of Neurology, University of Michigan, Ann Arbor, MI, United States.
  • Erin C Conrad
    Department of Neurology, Penn Epilepsy Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Kathryn A Davis
    Penn Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104; Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104.
  • Dan Roth
    Department of Computer and Information Science, School of Engineering and Applied Sciences, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Brian Litt
    Penn Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA, United States of America.
  • Colin A Ellis
    Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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