Modification of a Conventional Deep Learning Model to Classify Simulated Breathing Patterns: A Step toward Real-Time Monitoring of Patients with Respiratory Infectious Diseases.

Journal: Sensors (Basel, Switzerland)
PMID:

Abstract

The emergence of the global coronavirus pandemic in 2019 (COVID-19 disease) created a need for remote methods to detect and continuously monitor patients with infectious respiratory diseases. Many different devices, including thermometers, pulse oximeters, smartwatches, and rings, were proposed to monitor the symptoms of infected individuals at home. However, these consumer-grade devices are typically not capable of automated monitoring during both day and night. This study aims to develop a method to classify and monitor breathing patterns in real-time using tissue hemodynamic responses and a deep convolutional neural network (CNN)-based classification algorithm. Tissue hemodynamic responses at the sternal manubrium were collected in 21 healthy volunteers using a wearable near-infrared spectroscopy (NIRS) device during three different breathing conditions. We developed a deep CNN-based classification algorithm to classify and monitor breathing patterns in real time. The classification method was designed by improving and modifying the pre-activation residual network (Pre-ResNet) previously developed to classify two-dimensional (2D) images. Three different one-dimensional CNN (1D-CNN) classification models based on Pre-ResNet were developed. By using these models, we were able to obtain an average classification accuracy of 88.79% (without Stage 1 (data size reducing convolutional layer)), 90.58% (with 1 × 3 Stage 1), and 91.77% (with 1 × 5 Stage 1).

Authors

  • Jinho Park
    Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 49 Convent Dr., Bethesda, MD 20894, USA.
  • Aaron James Mah
    Implantable Biosensing Laboratory, International Collaboration on Repair Discoveries, Vancouver, BC V5Z 1M9, Canada.
  • Thien Nguyen
    Faculty of Information Technology, Ton Duc Thang University, Ho Chi Minh City, Vietnam.
  • Soongho Park
    Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 49 Convent Dr., Bethesda, MD 20894, USA.
  • Leili Ghazi Zadeh
    Implantable Biosensing Laboratory, International Collaboration on Repair Discoveries, Vancouver, BC V5Z 1M9, Canada.
  • Babak Shadgan
    Implantable Biosensing Laboratory, International Collaboration on Repair Discoveries, Vancouver, BC V5Z 1M9, Canada.
  • Amir H Gandjbakhche
    National Institute of Child Health and Human Development National Institutes of Health Bethesda MD USA.