Survival analysis using deep learning with medical imaging.

Journal: The international journal of biostatistics
Published Date:

Abstract

There is widespread interest in using deep learning to build prediction models for medical imaging data. These deep learning methods capture the local structure of the image and require no manual feature extraction. Despite the importance of modeling survival in the context of medical data analysis, research on deep learning methods for modeling the relationship of imaging and time-to-event data is still under-developed. We provide an overview of deep learning methods for time-to-event outcomes and compare several deep learning methods to Cox model based methods through the analysis of a histology dataset of gliomas.

Authors

  • Samantha Morrison
    Department of Biostatistics, Brown University, Providence, Rhode Island, USA.
  • Constantine Gatsonis
    Department of Biostatistics, Brown University, Providence, Rhode Island, USA.
  • Ani Eloyan
    Department of Biostatistics, School of Public Health, Brown University, Providence, RI, USA.
  • Jon Arni Steingrimsson
    Department of Biostatistics, Brown University, Providence, Rhode Island, USA.