Clinical target volume delineation quality assurance for MRI-guided prostate radiotherapy using deep learning with uncertainty estimation.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
PMID: 37414257

Abstract

BACKGROUND AND PURPOSE: Previous studies on automatic delineation quality assurance (QA) have mostly focused on CT-based planning. As MRI-guided radiotherapy is increasingly utilized in prostate cancer treatment, there is a need for more research on MRI-specific automatic QA. This work proposes a clinical target volume (CTV) delineation QA framework based on deep learning (DL) for MRI-guided prostate radiotherapy.

Authors

  • Hang Min
    South Western Sydney Clinical School, University of New South Wales, Sydney, New South Wales, Australia.
  • Jason Dowling
    Australian e-Health Research Centre, CSIRO, Digital Productivity Flagship.
  • Michael G Jameson
    St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Australia.
  • Kirrily Cloak
    Ingham Institute for Applied Medical Research, Sydney, New South Wales, Australia.
  • Joselle Faustino
    Liverpool and Macarthur Cancer therapy Centres, Liverpool Hospital, New South Wales, Australia.
  • Mark Sidhom
    South Western Clinical School, University of New South Wales, Australia.
  • Jarad Martin
    Department of Radiation Oncology, Calvary Mater Newcastle, Newcastle, New South Wales, Australia.
  • Michael Cardoso
    Liverpool and Macarthur Cancer therapy Centres, Liverpool Hospital, New South Wales, Australia.
  • Martin A Ebert
    School of Physics, University of Western Australia, Western Australia 6009, Australia and Department of Radiation Oncology, Sir Charles Gairdner Hospital, Western Australia 6008, Australia.
  • Annette Haworth
    The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia.
  • Phillip Chlap
    South Western Sydney Clinical School, University of New South Wales, Sydney, New South Wales, Australia.
  • Jeremiah de Leon
    GenesisCare, Sydney, New South Wales, Australia.
  • Megan Berry
    South Western Clinical School, University of New South Wales, Australia.
  • David Pryor
    Department of Radiation Oncology, Princess Alexandra Hospital, Brisbane, Australia; School of Medicine, University of Queensland, Australia.
  • Peter Greer
    School of Mathematical and Physical Sciences, University of Newcastle, New South Wales, Australia.
  • Shalini K Vinod
    Ingham Institute for Applied Medical Research, Sydney, New South Wales, Australia.
  • Lois Holloway
    d Cancer Therapy Centre, Liverpool Hospital , Liverpool , NSW , Australia.

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