Deep learning-based solid component measuring enabled interpretable prediction of tumor invasiveness for lung adenocarcinoma.

Journal: Lung cancer (Amsterdam, Netherlands)
Published Date:

Abstract

BACKGROUND: The nature of the solid component of subsolid nodules (SSNs) can indicate tumor pathological invasiveness. However, preoperative solid component assessment still lacks a reference standard.

Authors

  • Jiajing Sun
    Taizhou Hospital, Zhejiang University School of Medicine, Taizhou, China.
  • Li Zhang
    Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
  • Bingyu Hu
    Department of Thoracic Surgery, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, China.
  • Zhicheng Du
    Department of Medical Statistics and Epidemiology & Health Information Research Center & Guangdong Key Laboratory of Medicine, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
  • William C Cho
    Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong, SAR China.
  • Pasan Witharana
    Northern General Hospital, Herries Rd, Sheffield S5 7AU, UK; Imperial College London, London SW7 2BX, UK.
  • Hua Sun
    Taizhou Hospital, Zhejiang University School of Medicine, Taizhou, China.
  • Dehua Ma
    Department of Thoracic Surgery, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, China.
  • Minhua Ye
    Department of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, China.
  • Jiajun Chen
    Dianei Technology, Shanghai, P.R. China.
  • Xiaozhuang Wang
    Dianei Technology, Shanghai, China.
  • Jiancheng Yang
    Department of Electronic Engineering, Shanghai Jiao Tong University, Shanghai, P.R. China.
  • Chengchu Zhu
    Taizhou Hospital, Zhejiang University School of Medicine, Taizhou, China; Department of Thoracic Surgery, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, China. Electronic address: zhucc@enzemed.com.
  • Jianfei Shen
    Taizhou Hospital, Zhejiang University School of Medicine, Taizhou, China; Department of Thoracic Surgery, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, China. Electronic address: jianfei051@163.com.