AIMC Topic: Neoplasm Invasiveness
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Unraveling the role of perineural invasion in cancer progression across multiple tumor types.
Medical oncology (Northwood, London, England)
Jun 26, 2025
Perineural invasion (PNI) refers to the infiltration of tumor cells into the connective tissue of nerves and is increasingly recognized as a pathological hallmark of multiple cancers, including pancreatic, prostate, colorectal, breast, and head and n...
Harnessing the machine learning and nomogram models: elevating prognostication in nonmetastatic gastric cancer with "double invasion" for personalized patient care.
European journal of medical research
Jun 23, 2025
OBJECTIVE: To develop and validate a machine learning framework combined with a nomogram for predicting recurrence after radical gastrectomy in patients with vascular and neural invasion.
Dual-energy CT combined with histogram parameters in the assessment of perineural invasion in colorectal cancer.
International journal of colorectal disease
May 27, 2025
PURPOSE: The purpose is to evaluate the predictive value of dual-energy CT (DECT) combined with histogram parameters and a clinical prediction model for perineural invasion (PNI) in colorectal cancer (CRC).
AI-based multimodal prediction of lymph node metastasis and capsular invasion in cT1N0M0 papillary thyroid carcinoma.
Frontiers in endocrinology
May 27, 2025
BACKGROUND: Accurate preoperative evaluation of cT1N0M0 papillary thyroid carcinoma (PTC) is essential for guiding appropriate treatment strategies. Although ultrasound is widely used for clinical staging, it has limitations in detecting lymph node m...
MSFusion: A multi-source hybrid feature fusion network for accurate grading of invasive breast cancer using H&E-stained histopathological images.
Medical image analysis
May 23, 2025
Invasive breast cancer (IBC) is a prevalent malignant tumor in women, and precise grading plays a pivotal role in ensuring effective treatment and enhancing survival rates. However, accurately grading IBC presents a significant challenge due to its h...
Tumor budding and poorly differentiated clusters as a biological continuum in colorectal cancer invasion and prognosis.
Scientific reports
May 15, 2025
Tumor budding (TB) and poorly differentiated clusters (PDCs) are features of infiltrative growth patterns and powerful independent prognostic factors in colorectal cancer (CRC), yet the underlying biological mechanisms behind their role in CRC invasi...
Preoperative Prediction of Microvascular Invasion in Hepatocellular Carcinoma From Multi-Sequence Magnetic Resonance Imaging Based on Deep Fusion Representation Learning.
IEEE journal of biomedical and health informatics
May 6, 2025
Recent studies have identified microvascular invasion (MVI) as the most vital independent biomarker associated with early tumor recurrence. With advancements in medical technology, several computational methods have been developed to predict preopera...
Preoperative lymph node metastasis risk assessment in invasive micropapillary carcinoma of the breast: development of a machine learning-based predictive model with a web-based calculator.
World journal of surgical oncology
Apr 22, 2025
BACKGROUND: Invasive micropapillary carcinoma (IMPC) is a rare subtype of breast cancer characterized by a high risk of lymph node metastasis (LNM). The study aimed to identify predictors of LNM and to develop a machine learning (ML)-based risk predi...
Updated perspectives on visceral pleural invasion in non-small cell lung cancer: A propensity score-matched analysis of the SEER database.
Current problems in cancer
Apr 18, 2025
BACKGROUND: Visceral pleural invasion (VPI), including PL1 (the tumor invades beyond the elastic layer) and PL2 (the tumor extends to the surface of the visceral pleura), plays a crucial role in staging Non-Small Cell Lung Cancer (NSCLC). However, th...
Development and validation of interpretable machine learning models to predict distant metastasis and prognosis of muscle-invasive bladder cancer patients.
Scientific reports
Apr 6, 2025
Muscle-Invasive Bladder Cancer (MIBC) is a more aggressive disease than non-muscle-invasive bladder cancer (NMIBC), with greater chances of metastasis. We sought to develop machine learning (ML) models to predict metastasis and prognosis in MIBC pati...
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