Multimodal hybrid convolutional neural network based brain tumor grade classification.

Journal: BMC bioinformatics
Published Date:

Abstract

An abnormal growth or fatty mass of cells in the brain is called a tumor. They can be either healthy (normal) or become cancerous, depending on the structure of their cells. This can result in increased pressure within the cranium, potentially causing damage to the brain or even death. As a result, diagnostic procedures such as computed tomography, magnetic resonance imaging, and positron emission tomography, as well as blood and urine tests, are used to identify brain tumors. However, these methods can be labor-intensive and sometimes yield inaccurate results. Instead of these time-consuming methods, deep learning models are employed because they are less time-consuming, require less expensive equipment, produce more accurate results, and are easy to set up. In this study, we propose a method based on transfer learning, utilizing the pre-trained VGG-19 model. This approach has been enhanced by applying a customized convolutional neural network framework and combining it with pre-processing methods, including normalization and data augmentation. For training and testing, our proposed model used 80% and 20% of the images from the dataset, respectively. Our proposed method achieved remarkable success, with an accuracy rate of 99.43%, a sensitivity of 98.73%, and a specificity of 97.21%. The dataset, sourced from Kaggle for training purposes, consists of 407 images, including 257 depicting brain tumors and 150 without tumors. These models could be utilized to develop clinically useful solutions for identifying brain tumors in CT images based on these outcomes.

Authors

  • A Rohini
    Department of Computer Science and Engineering, Anil Neerukonda Institute of Technology and Sciences, Vishakapatnam, Andhra Pradesh, 531162, India.
  • Carol Praveen
    Department of Electronics and Communication Engineering, SSM Institute of Engineering and Technology, Dindigul, Tamilnadu, India.
  • Sandeep Kumar Mathivanan
    School of Information Technology and Engineering, Vellore Institute of Technology, Vellore, India.
  • V Muthukumaran
    Department of Mathematics, College of Engineering and Technology, SRM Institute of Science and Technology, Kattankulathur, Tamilnadu, 603203, India.
  • Saurav Mallik
    Center for Precision Health, School of Biomedical Informatics, The University of Texas Health Science Center, Houston.
  • Mohammed S Alqahtani
    Radiological Sciences Department, College of Applied Medical Sciences, King Khalid University, Abha 61421, Saudi Arabia.
  • Amal Al-Rasheed
    Department of Information Systems, College of Computer and Information Sciences, Princess Nourah bint Abdulrahman University, P.O. Box 84428, 11671, Riyadh, Saudi Arabia.
  • Ben Othman Soufiene
    PRINCE Laboratory Research, ISITcom, Hammam Sousse, University of Sousse, Sousse 4023, Tunisia.