Predicting Visual Acuity Responses to Anti-VEGF Treatment in the Comparison of Age-related Macular Degeneration Treatments Trials Using Machine Learning.

Journal: Ophthalmology. Retina
PMID:

Abstract

PURPOSE: To evaluate multiple machine learning (ML) models for predicting 2-year visual acuity (VA) responses to anti-vascular endothelial growth factor (anti-VEGF) treatment in the Comparison of Age-related Macular Degeneration (AMD) Treatments Trials (CATT) for patients with neovascular AMD (nAMD).

Authors

  • Rajat S Chandra
    Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Gui-Shuang Ying
    Department of Ophthalmology, Center for Preventive Ophthalmology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: gsying@pennmedicine.upenn.edu.