Association Between Genotypes and Risk of Cardiovascular Disease in MESA (Multi-Ethnic Study of Atherosclerosis).

Journal: Journal of the American Heart Association
Published Date: Dec 21, 2017

Abstract

BACKGROUND: genetic variants confer an increased risk for kidney disease. Their associations with cardiovascular disease (CVD) are less certain. We aimed to compare the prevalence of subclinical CVD and incidence of atherosclerotic CVD and heart failure by genotypes among self-identified black participants of MESA (Multi-Ethnic Study of Atherosclerosis).

Authors

  • Teresa K Chen
    Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD tchen39@jhmi.edu.
  • Ronit Katz
    Department of Medicine, Kidney Research Institute, University of Washington, Seattle, WA.
  • Michelle M Estrella
    Kidney Health Research Collaborative, Department of Medicine, University of California, San Francisco, CA.
  • Orlando M Gutierrez
    Departments of Medicine and Epidemiology, University of Alabama at Birmingham, AL.
  • Holly Kramer
    Division of Nephrology, Departments of Medicine and Public Health Sciences, Loyola University, Maywood, IL.
  • Wendy S Post
    Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD.
  • Michael G Shlipak
    Kidney Health Research Collaborative, San Francisco VA Medical Center, University of California, San Francisco, CA, USA.
  • Christina L Wassel
    Department of Pathology and Laboratory Medicine, University of Vermont College of Medicine, Colchester, VT.
  • Carmen A Peralta
    Kidney Health Research Collaborative, Department of Medicine, University of California, San Francisco, CA.

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