Automated evaluation with deep learning of total interstitial inflammation and peritubular capillaritis on kidney biopsies.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
PMID:

Abstract

BACKGROUND: Interstitial inflammation and peritubular capillaritis are observed in many diseases on native and transplant kidney biopsies. A precise and automated evaluation of these histological criteria could help stratify patients' kidney prognoses and facilitate therapeutic management.

Authors

  • Amélie Jacq
    Department of Nephrology, CHU Dijon, Dijon, France.
  • Georges Tarris
    Université de Bourgogne Franche comté, France.
  • Adrien Jaugey
    Université de Bourgogne Franche comté, France.
  • Michel Paindavoine
    Université de Bourgogne Franche comté, France.
  • Elise Marechal
    Department of Nephrology, CHU Dijon, France.
  • Patrick Bard
    ESIREM School, Dijon, France.
  • Jean-Michel Rebibou
    Department of Nephrology, CHU Dijon, France.
  • Manon Ansart
    Institut du Cerveau, ICM, Inserm U 1127, CNRS UMR 7225, Sorbonne Université, F75013, Paris, France; Inria, Aramis project-team, F-75013, Paris, France.
  • Doris Calmo
    Department of Nephrology, CHU Besançon, Besançon, France.
  • Jamal Bamoulid
    UMR 1098, INCREASE, Besançon, France.
  • Claire Tinel
    Department of Microbiology, Immunology and Transplantation, Nephrology and Kidney Transplantation Research Group, KU Leuven, Leuven, Belgium.
  • Didier Ducloux
    Université de Bourgogne Franche comté, France.
  • Thomas Crepin
    Département de Néphrologie, Dialyse et Transplantation, CHU de Besançon, Besançon, France.
  • Melchior Chabannes
    Department of Nephrology, CHU Besançon, Besançon, France.
  • Mathilde Funes de la Vega
    Department of Pathology, CHU Dijon, France.
  • Sophie Felix
    Department of Pathology, CHU Besançon France.
  • Laurent Martin
    Université de Bourgogne Franche comté, France.
  • Mathieu Legendre
    Department of Nephrology, CHU Dijon, France.