Cortico-cortical stimulation and robot-assisted therapy (CCS and RAT) for upper limb recovery after stroke: study protocol for a randomised controlled trial.

Journal: Trials
Published Date: Dec 21, 2023

Abstract

BACKGROUND: Since birth, during the exploration of the environment to interact with objects, we exploit both the motor and sensory components of the upper limb (UL). This ability to integrate sensory and motor information is often compromised following a stroke. However, to date, rehabilitation protocols are focused primarily on recovery of motor function through physical therapies. Therefore, we have planned a clinical trial to investigate the effect on functionality of UL after a sensorimotor transcranial stimulation (real vs sham) in add-on to robot-assisted therapy in the stroke population.

Authors

  • Alex Martino Cinnera
    Scientific Institute for Research, Hospitalization and Health Care IRCCS Santa Lucia Foundation, Rome, Italy. a.martino@hsantalucia.it.
  • Sonia Bonnì
    Scientific Institute for Research, Hospitalization and Health Care IRCCS Santa Lucia Foundation, Rome, Italy.
  • Alessia D'Acunto
    Scientific Institute for Research, Hospitalization and Health Care IRCCS Santa Lucia Foundation, Rome, Italy.
  • Michele Maiella
    Scientific Institute for Research, Hospitalization and Health Care IRCCS Santa Lucia Foundation, Rome, Italy.
  • Matteo Ferraresi
    Scientific Institute for Research, Hospitalization and Health Care IRCCS Santa Lucia Foundation, Rome, Italy.
  • Elias Paolo Casula
    Scientific Institute for Research, Hospitalization and Health Care IRCCS Santa Lucia Foundation, Rome, Italy.
  • Valentina Pezzopane
    Scientific Institute for Research, Hospitalization and Health Care IRCCS Santa Lucia Foundation, Rome, Italy.
  • Marco Tramontano
    I.R.C.C.S. Santa Lucia Foundation (FSL), Via Ardeatina, 306, 00179, Rome, Italy.
  • Marco Iosa
    Clinical Laboratory of Experimental Neurorehabilitation, I.R.C.C.S, Fondazione Santa Lucia, Rome, Italy.
  • Stefano Paolucci
    Clinical Laboratory of Experimental Neurorehabilitation, I.R.C.C.S, Fondazione Santa Lucia, Rome, Italy.
  • Giovanni Morone
    Clinical Laboratory of Experimental Neurorehabilitation, I.R.C.C.S, Fondazione Santa Lucia, Rome, Italy. g.morone@hsantalucia.it.
  • Giuseppe Vannozzi
    Scientific Institute for Research, Hospitalization and Health Care IRCCS Santa Lucia Foundation, Rome, Italy.
  • Giacomo Koch
    Non Invasive Brain Stimulation Unit, Department of Behavioral and Clinical Neurology, Santa Lucia Foundation IRCCS, 00179 Rome, Italy.

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