Cognitive sequelae of endocrine therapy in women treated for breast cancer: a meta-analysis.

Journal: Breast cancer research and treatment
PMID: 29264751

Abstract

PURPOSE: Evidence suggests anti-estrogen endocrine therapy (ET) is associated with adverse cognitive effects; however, findings are based on small samples and vary in the cognitive abilities affected. We conducted a meta-analysis to quantitatively synthesize the evidence.

Authors

  • E A Underwood
    Institute of Medical Science, University of Toronto, Toronto, ON, Canada.
  • P A Rochon
    Institute of Medical Science, University of Toronto, Toronto, ON, Canada.
  • R Moineddin
    Department of Family and Community Medicine, University of Toronto, Toronto, ON, Canada.
  • P E Lee
    Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
  • W Wu
    Women's College Research Institute, Women's College Hospital, Toronto, ON, Canada.
  • K I Pritchard
    Department of Medicine, University of Toronto, Toronto, ON, Canada.
  • M C Tierney
    Department of Family and Community Medicine, University of Toronto, Toronto, ON, Canada. mary.tierney@sunnybrook.ca.

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