Deep learning-based whole-body characterization of prostate cancer lesions on [Ga]Ga-PSMA-11 PET/CT in patients with post-prostatectomy recurrence.

Journal: European journal of nuclear medicine and molecular imaging
PMID: 38049657

Abstract

PURPOSE: The automatic segmentation and detection of prostate cancer (PC) lesions throughout the body are extremely challenging due to the lesions' complexity and variability in appearance, shape, and location. In this study, we investigated the performance of a three-dimensional (3D) convolutional neural network (CNN) to automatically characterize metastatic lesions throughout the body in a dataset of PC patients with recurrence after radical prostatectomy.

Authors

  • Bingsheng Huang
    School of Biomedical Engineering, Shenzhen University Health Sciences Center, Shenzhen, Guangdong 518060, P.R.China.
  • Qinqin Yang
    Institute of Laser and Optoelectronics Technology, Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou, China.
  • Xiao Li
    Department of Inner Mongolia Clinical Medicine College, Inner Mongolia Medical University, Hohhot, Inner Mongolia, China.
  • Yuxuan Wu
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Vision Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.
  • Zhantao Liu
    Medical AI Lab, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen, China.
  • Zhaohong Pan
    Medical AI Lab, School of Biomedical Engineering, Health Science Centre, Shenzhen University, Shenzhen, China.
  • Shaonan Zhong
    Medical AI Lab, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen, China. snzhong@qq.com.
  • Shaoli Song
    Department of Nuclear Medicine, Fudan University Shanghai Cancer Center, Shanghai, 200032, China. shaoli-song@163.com.
  • Changjing Zuo
    Department of Nuclear Medicine, The First Affiliated Hospital of Naval Medical University (Changhai Hospital), 168 Changhai Road, Shanghai, 200433, China.

Keywords

External Resources

Popular Topics
Recent Journals