AIMC Topic: Gallium Radioisotopes

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PSMA PET Evaluation with a Deep Learning Platform Compared with a Standard Image Viewer and Histopathology.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Standardized prostate-specific membrane antigen (PSMA) PET/CT evaluation and reporting was introduced to aid interpretation, reproducibility, and communication. Artificial intelligence may enhance these efforts. This study aimed to evaluate the perfo...

Deep Learning for Automated Measures of SUV and Molecular Tumor Volume in [Ga]PSMA-11 or [F]DCFPyL, [F]FDG, and [Lu]Lu-PSMA-617 Imaging with Global Threshold Regional Consensus Network.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Metastatic castration-resistant prostate cancer has a high rate of mortality with a limited number of effective treatments after hormone therapy. Radiopharmaceutical therapy with [Lu]Lu-prostate-specific membrane antigen-617 (LuPSMA) is one treatment...

[Ga]Ga-PSMA-11 PET Tumor Volume Predicts Overall Survival of Patients with Metastatic Prostate Cancer Undergoing Taxane-Based Chemotherapy.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Prostate-specific membrane antigen (PSMA) PET has the potential to monitor the response to taxane-based chemotherapy in patients with prostate cancer and shows promise for predicting outcomes and improving response evaluation. This retrospective stud...

Reconstruction of total-body multi parametric images with shortened-duration dynamic [Ga]Ga-PSMA-11 and [Ga]Ga-FAPI-04 PET scans.

Physics in medicine and biology
The lengthy 1 h dynamic positron emission tomography (PET) scans discomfort patients, add motion artifacts, and inflate costs, highlighting the need for tech advancements to reduce scan times. Therefore, we attempted to reconstruct multi-parametric i...

The Use of Maximum-Intensity Projections and Deep Learning Adds Value to the Fully Automatic Segmentation of Lesions Avid for [F]FDG and [Ga]Ga-PSMA in PET/CT.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
This study investigated the added value of using maximum-intensity projection (MIP) images for fully automatic segmentation of lesions using deep learning (DL) in [F]FDG and [Ga]Ga-prostate-specific membrane antigen (PSMA) PET/CT scans. We used 489 ...

Machine learning models for enhanced diagnosis and risk assessment of prostate cancer with Ga-PSMA-617 PET/CT.

European journal of radiology
OBJECTIVE: Prostate cancer (PCa) is highly heterogeneous, making early detection of adverse pathological features crucial for improving patient outcomes. This study aims to predict PCa aggressiveness and identify radiomic and protein biomarkers assoc...

The Value of Machine Learning-based Radiomics Model Characterized by PET Imaging with Ga-FAPI in Assessing Microvascular Invasion of Hepatocellular Carcinoma.

Academic radiology
RATIONALE AND OBJECTIVES: This study aimed to develop a radiomics model characterized by Ga-fibroblast activation protein inhibitors (FAPI) positron emission tomography (PET) imaging to predict microvascular invasion (MVI) of hepatocellular carcinoma...

Multi-modality deep learning-based [Ga]Ga-DOTA-FAPI-04 PET polar map generation: potential value in detecting reactive fibrosis after myocardial infarction.

European journal of nuclear medicine and molecular imaging
PURPOSE: Generating polar map (PM) from [Ga]Ga-DOTA-FAPI-04 PET images is challenging and inaccurate using existing automatic methods that rely on the myocardial anatomical integrity in PET images. This study aims to enhance the accuracy of PM genera...