AIMC Topic: Gallium Isotopes
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The Use of Maximum-Intensity Projections and Deep Learning Adds Value to the Fully Automatic Segmentation of Lesions Avid for [F]FDG and [Ga]Ga-PSMA in PET/CT.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
May 1, 2025
This study investigated the added value of using maximum-intensity projection (MIP) images for fully automatic segmentation of lesions using deep learning (DL) in [F]FDG and [Ga]Ga-prostate-specific membrane antigen (PSMA) PET/CT scans. We used 489 ...
Machine learning models for enhanced diagnosis and risk assessment of prostate cancer with Ga-PSMA-617 PET/CT.
European journal of radiology
Mar 19, 2025
OBJECTIVE: Prostate cancer (PCa) is highly heterogeneous, making early detection of adverse pathological features crucial for improving patient outcomes. This study aims to predict PCa aggressiveness and identify radiomic and protein biomarkers assoc...
Dipeptides
Biomarkers, Tumor
Gallium Radioisotopes
Retrospective Studies
Male
Positron Emission Tomography Computed Tomography
Gallium Isotopes
Aged
Middle Aged
Heterocyclic Compounds, 1-Ring
Prostatic Neoplasms
Aged, 80 and over
Risk Assessment
Prostate-Specific Antigen
Sensitivity and Specificity
Humans
Radiopharmaceuticals
Machine Learning
Evaluation of the prostate cancer and its metastases in the [ 68 Ga]Ga-PSMA PET/CT images: deep learning method vs. conventional PET/CT processing.
Nuclear medicine communications
Sep 3, 2024
PURPOSE: This study demonstrates the feasibility and benefits of using a deep learning-based approach for attenuation correction in [ 68 Ga]Ga-PSMA PET scans.
Machine learning-based analysis of Ga-PSMA-11 PET/CT images for estimation of prostate tumor grade.
Physical and engineering sciences in medicine
Mar 25, 2024
Early diagnosis of prostate cancer, the most common malignancy in men, can improve patient outcomes. Since the tissue sampling procedures are invasive and sometimes inconclusive, an alternative image-based method can prevent possible complications an...
Deep learning-based whole-body characterization of prostate cancer lesions on [Ga]Ga-PSMA-11 PET/CT in patients with post-prostatectomy recurrence.
European journal of nuclear medicine and molecular imaging
Dec 5, 2023
PURPOSE: The automatic segmentation and detection of prostate cancer (PC) lesions throughout the body are extremely challenging due to the lesions' complexity and variability in appearance, shape, and location. In this study, we investigated the perf...
Prostate-specific membrane antigen Radioguided Surgery to Detect Nodal Metastases in Primary Prostate Cancer Patients Undergoing Robot-assisted Radical Prostatectomy and Extended Pelvic Lymph Node Dissection: Results of a Planned Interim Analysis of a Prospective Phase 2 Study.
European urology
Jul 22, 2022
BACKGROUND: Extended pelvic nodal dissection (ePLND) represents the gold standard for nodal staging in prostate cancer (PCa). Prostate-specific membrane antigen (PSMA) radioguided surgery (RGS) could identify lymph node invasion (LNI) during robot-as...
Tc-PSMA targeted robot-assisted radioguided surgery during radical prostatectomy and extended lymph node dissection of prostate cancer patients.
Annals of nuclear medicine
Apr 15, 2022
OBJECTIVE: The feasibility of tracer production of technetium (Tc)-prostate-specific membrane antigen (PSMA)-I&S sterile cold kit, imaging with single photon emission tomography/computed tomography (SPECT/CT), and Tc-PSMA-radioguided robot-assisted l...
Radiation Protection and Occupational Exposure on Ga-PSMA-11-Based Cerenkov Luminescence Imaging Procedures in Robot-Assisted Prostatectomy.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Dec 16, 2021
Cerenkov luminescence imaging (CLI) was successfully implemented in the intraoperative context as a form of radioguided cancer surgery, showing promise in the detection of surgical margins during robot-assisted radical prostatectomy. The present stud...
Intraprostatic Tumor Segmentation on PSMA PET Images in Patients with Primary Prostate Cancer with a Convolutional Neural Network.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Oct 30, 2020
Accurate delineation of the intraprostatic gross tumor volume (GTV) is a prerequisite for treatment approaches in patients with primary prostate cancer (PCa). Prostate-specific membrane antigen PET (PSMA PET) may outperform MRI in GTV detection. Howe...
Prostate Cancer Nodal Staging: Using Deep Learning to Predict Ga-PSMA-Positivity from CT Imaging Alone.
Scientific reports
Feb 25, 2020
Lymphatic spread determines treatment decisions in prostate cancer (PCa) patients. 68Ga-PSMA-PET/CT can be performed, although cost remains high and availability is limited. Therefore, computed tomography (CT) continues to be the most used modality f...
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