Deep learning models for automatic tumor segmentation and total tumor volume assessment in patients with colorectal liver metastases.

Journal: European radiology experimental
Published Date:

Abstract

BACKGROUND: We developed models for tumor segmentation to automate the assessment of total tumor volume (TTV) in patients with colorectal liver metastases (CRLM).

Authors

  • Nina J Wesdorp
    Department of Surgery, Cancer Center Amsterdam, Amsterdam University Medical Centers, Vrije Universiteit, Amsterdam, The Netherlands. n.wesdorp@amsterdamumc.nl.
  • J Michiel Zeeuw
    Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands. j.m.zeeuw@amsterdamumc.nl.
  • Sam C J Postma
    Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands.
  • Joran Roor
    Department of Health, SAS Institute B.V, Huizen, the Netherlands.
  • Jan Hein T M van Waesberghe
    Department of Radiology and Nuclear Medicine, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
  • Janneke E van den Bergh
    Department of Radiology and Nuclear Medicine, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
  • Irene M Nota
    Department of Radiology and Nuclear Medicine, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
  • Shira Moos
    Department of Radiology and Nuclear Medicine, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
  • Ruby Kemna
    Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands.
  • Fijoy Vadakkumpadan
    Department of Computer Vision and Machine Learning, SAS Institute Inc, Cary, NC, USA.
  • Courtney Ambrozic
    Department of Computer Vision and Machine Learning, SAS Institute Inc, Cary, NC, USA.
  • Susan van Dieren
    Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands.
  • Martinus J van Amerongen
    Department of Radiology, Sint Maartenskliniek, Nijmegen, the Netherlands.
  • Thiery Chapelle
    Department of Hepatobiliary, Transplantation, and Endocrine Surgery, Antwerp University Hospital, Antwerp, Belgium.
  • Marc R W Engelbrecht
    Department of Radiology and Nuclear Medicine, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
  • Michael F Gerhards
    Department of Surgery, OLVG Hospital, Amsterdam, the Netherlands.
  • Dirk Grunhagen
    Department of Surgical Oncology and Gastrointestinal Surgery, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
  • Thomas M van Gulik
    Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands.
  • John J Hermans
    Department of Medical Imaging, Radboud University Medical Center, Radboud University Nijmegen, Nijmegen, the Netherlands.
  • Koert P de Jong
    Department of HPB Surgery and Liver Transplantation, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Joost M Klaase
    Department of Surgery, Medisch Spectrum Twente, Enschede, The Netherlands.
  • Mike S L Liem
    Department of Surgery, Medisch Spectrum Twente, Enschede, The Netherlands, Koningsstraat 1, Po-Box 50000, 7500 KA, Enschede, the Netherlands. Electronic address: M.Liem@mst.nl.
  • Krijn P van Lienden
    Department of Interventional Radiology, St Antonius Hospital, Nieuwegein, the Netherlands.
  • I Quintus Molenaar
    Department of Surgery, Regional Academic Cancer Center Utrecht, UMC Utrecht Cancer Center and St Antonius Hospital Nieuwegein, Utrecht University, Utrecht, the Netherlands.
  • Gijs A Patijn
    Department of Surgery, Isala Hospital, Zwolle, the Netherlands.
  • Arjen M Rijken
    Department of Surgery, Amphia Hospital, Breda, the Netherlands.
  • Theo M Ruers
    Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands.
  • Cornelis Verhoef
    Department of Surgical Oncology and Gastrointestinal Surgery, Erasmus MC Cancer Centre, University Medical Centre Rotterdam, the Netherlands.
  • Johannes H W de Wilt
    Department of Surgery, Radboud University Medical Center, Radboud University Nijmegen, Nijmegen, the Netherlands.
  • Henk A Marquering
    Department of Biomedical Engineering and Physics, Academic Medical Center, Amsterdam, The Netherlands.
  • Jaap Stoker
    Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centers - location AMC, University of Amsterdam, Amsterdam, the Netherlands; Amsterdam Gastroenterology, Endocrinology and Metabolism, Amsterdam University Medical Centers - location AMC, Amsterdam, the Netherlands.
  • Rutger-Jan Swijnenburg
    Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands.
  • Cornelis J A Punt
    Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Joost Huiskens
    SAS Institute B.V, Huizen, The Netherlands.
  • Geert Kazemier
    Department of Surgery, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands.