Achalasia phenotypes and prediction of peroral endoscopic myotomy outcomes using machine learning.

Journal: Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society
PMID: 37886891

Abstract

OBJECTIVES: High-resolution manometry (HRM) and esophagography are used for achalasia diagnosis; however, achalasia phenotypes combining esophageal motility and morphology are unknown. Moreover, predicting treatment outcomes of peroral endoscopic myotomy (POEM) in treatment-naïve patients remains an unmet need.

Authors

  • Kazuya Takahashi
    Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
  • Hiroki Sato
    Department of Bioscience and Engineering, Shibaura Institute of Technology, Saitama, Saitama, 337-8570, Japan.
  • Yuto Shimamura
    Digestive Diseases Center, Showa University Koto-Toyosu Hospital, Tokyo, Japan.
  • Hirofumi Abe
    Department of Gastroenterology, Kobe University Hospital, Kobe, Japan.
  • Hironari Shiwaku
    Department of Gastroenterological Surgery, Fukuoka University Faculty of Medicine, Fukuoka, Japan.
  • Junya Shiota
    Department of Gastroenterology and Hepatology, Nagasaki University Hospital, Nagasaki, Japan.
  • Chiaki Sato
    Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midoriku Yokohama, 226-8503, Japan.
  • Kenta Hamada
    Department of Endoscopy, Okayama University Hospital, Okayama, Japan.
  • Masaki Ominami
    Department of Gastroenterology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
  • Yoshitaka Hata
    Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
  • Hisashi Fukuda
    Division of Gastroenterology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
  • Ryo Ogawa
    Agro-Ecological Modeling Group, Institute of Crop Science and Resource Conservation, University of Bonn, Bonn, Germany.
  • Jun Nakamura
    Department of Endoscopy, Fukushima Medical University Hospital, Fukushima, Japan.
  • Tetsuya Tatsuta
    Department of Gastroenterology and Hematology, Hirosaki University Graduate School of Medicine, Aomori, Japan.
  • Yuichiro Ikebuchi
    Division of Gastroenterology and Nephrology, Department of Multidisciplinary Internal Medicine, Tottori University Faculty of Medicine, Yonago, Japan.
  • Hiroshi Yokomichi
    Department of Health Sciences, University of Yamanashi, Yamanashi, Japan.
  • Shuji Terai
    Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
  • Haruhiro Inoue
    Showa University Koto-Toyosu Hospital, Tokyo, Japan (H.I.).

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