Shared diagnostic genes and potential mechanisms between polycystic ovary syndrome and recurrent miscarriage revealed by integrated transcriptomics analysis and machine learning.

Journal: Frontiers in endocrinology
PMID: 39398336

Abstract

OBJECTIVE: More and more studies have found that polycystic ovary syndrome (PCOS) is significantly associated with recurrent spontaneous abortion (RSA), but the specific mechanism is not yet clear.

Authors

  • Juanjuan He
    Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai Neurosurgical Clinical Center, Shanghai, China.
  • Ahui Liu
    The First School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China.
  • Haofei Shen
    The First Hospital of Lanzhou University, Lanzhou, Gansu, China.
  • Yanbiao Jiang
    The First School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China.
  • Min Gao
    Department of Biliary Surgery, West China Hospital of Sichuan University, Chengdu, China.
  • Liulin Yu
    The First Hospital of Lanzhou University, Lanzhou, Gansu, China.
  • Wenjing Du
  • Xuehong Zhang
    The First School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China.
  • Fen Fu
    The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.

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