Machine Learning-Aided Decision-Making Model for the Discontinuation of Continuous Renal Replacement Therapy.

Journal: Blood purification
PMID:

Abstract

INTRODUCTION: Continuous renal replacement therapy (CRRT) is a primary form of renal support for patients with acute kidney injury in an intensive care unit. Making an accurate decision of discontinuation is crucial for the prognosis of patients. Previous research has mostly focused on the univariate and multivariate analysis of factors in CRRT, without the capacity to capture the complexity of the decision-making process. The present study thus developed a dynamic, interpretable decision model for CRRT discontinuation.

Authors

  • Siyi Zhu
    Department of Computer Science, Xiamen University, Xiamen 361005, China.
  • Jing Yan
    Department of Neurology, Shanghai Pudong New Area People's Hospital, Shanghai, China.
  • Shijin Gong
    Department of Critical Care Medicine, Zhejiang Hospital, Hangzhou, China.
  • Xue Feng
    Department of Radiology and Medical Imaging, University of Virginia, Charlottesville, Virginia.
  • Gangmin Ning
    College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou 310027, P.R.China.
  • Liang Xu