Fully automated kidney image biomarker prediction in ultrasound scans using Fast-Unet+.

Journal: Scientific reports
Published Date:

Abstract

Any kidney dimension and volume variation can be a remarkable indicator of kidney disorders. Precise kidney segmentation in standard planes plays an undeniable role in predicting kidney size and volume. On the other hand, ultrasound is the modality of choice in diagnostic procedures. This paper proposes a convolutional neural network with nested layers, namely Fast-Unet++, promoting the Fast and accurate Unet model. First, the model was trained and evaluated for segmenting sagittal and axial images of the kidney. Then, the predicted masks were used to estimate the kidney image biomarkers, including its volume and dimensions (length, width, thickness, and parenchymal thickness). Finally, the proposed model was tested on a publicly available dataset with various shapes and compared with the related networks. Moreover, the network was evaluated using a set of patients who had undergone ultrasound and computed tomography. The dice metric, Jaccard coefficient, and mean absolute distance were used to evaluate the segmentation step. 0.97, 0.94, and 3.23 mm for the sagittal frame, and 0.95, 0.9, and 3.87 mm for the axial frame were achieved. The kidney dimensions and volume were evaluated using accuracy, the area under the curve, sensitivity, specificity, precision, and F1.

Authors

  • Mostafa Ghelich Oghli
    Research and Development Department, Med Fanavarn Plus Co., Karaj, Iran; Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Science, Tehran, Iran. Electronic address: m.g31.mesu@gmail.com.
  • Seyed Morteza Bagheri
    Department of Radiology, Hasheminejad Kidney Center, Iran University of Medical Sciences, Tehran, Iran.
  • Ali Shabanzadeh
    Research and Development Department, Med Fanavarn Plus Co., Karaj, Iran. Electronic address: shabanzadeh.ali@gmail.com.
  • Mohammad Zare Mehrjardi
    Section of Body Imaging, Division of Clinical Research, Climax Radiology Education Foundation, Tehran, Iran.
  • Ardavan Akhavan
    Research and Development Department, Med Fanavarn Plus Co., Karaj, Iran.
  • Isaac Shiri
    Biomedical and Health Informatics, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
  • Mostafa Taghipour
    Department of Biomedical Engineering, Kermanshah University of Medical Sciences, Kermanshah, Iran.
  • Zahra Shabanzadeh
    School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.