An advanced machine learning method for simultaneous breast cancer risk prediction and risk ranking in Chinese population: A prospective cohort and modeling study.

Journal: Chinese medical journal
Published Date:

Abstract

BACKGROUND: Breast cancer (BC) risk-stratification tools for Asian women that are highly accurate and can provide improved interpretation ability are lacking. We aimed to develop risk-stratification models to predict long- and short-term BC risk among Chinese women and to simultaneously rank potential non-experimental risk factors.

Authors

  • Liyuan Liu
    State Key Laboratory of Superlattices and Microstructures, Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083, China.
  • Yong He
    College of Biosystems Engineering and Food Science, Zhejiang Univ., Hangzhou, 310058, China.
  • Chunyu Kao
    Zhongtai Securities Institute for Financial Studies, Shandong University, Jinan, Shandong 250100, China.
  • Yeye Fan
    School of Mathematics, Shandong University, Jinan, Shandong 250100, China.
  • Fu Yang
    College of Science, Donghua University, Shanghai 201620, China.
  • Fei Wang
    Department of Population Health Sciences, Weill Cornell Medicine, Cornell University, New York, NY, United States.
  • Lixiang Yu
    Department of Breast Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250033, China.
  • Fei Zhou
    College of Information Science and Engineering, Xinjiang University, Urumqi 830046, China.
  • Yujuan Xiang
    Department of Breast Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250033, China.
  • Shuya Huang
    Department of Breast Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250033, China.
  • Chao Zheng
    School of Biomedical Engineering, Southern Medical University, Guangzhou, Guangdong 510515 People's Republic of China.
  • Han Cai
    Department of Breast Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250033, China.
  • Heling Bao
    Department of Maternal and Child Health, School of Public Health, Peking University, Beijing, China.
  • Liwen Fang
    National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
  • Linhong Wang
    Landing Cloud Medical Laboratory Co., Wuhan, China.
  • Zengjing Chen
    School of Mathematics, Shandong University, Jinan, Shandong 250100, China.
  • Zhigang Yu
    Department of Biomedical Engineering, ShenZhen University, ShenZhen, 518000, China.