[Sodium Ferulate Attenuates Oxidative Stressvia Suppressing NALP3 Inflammasome and ERK Signal Pathway].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
PMID:

Abstract

OBJECTIVES: Study the gene and protein expression of NACHT-PYD-containing protein 3 (NALP3) inflammasome and extracellular regulated protein kinase (ERK), the intervention effects of sodium ferulate (SF) in human lung epithelial cells A549 under oxidative stress, and to investigate the possible mechanism.

Authors

  • Xiao-Lin Wei
    Department of Respiratory Disease, West China Hospital, Sichuan University, Chengdu 610041,China.
  • Min Xie
    Department of Respiratory Disease, West China Hospital, Sichuan University, Chengdu 610041,China.
  • Gao-Yan He
    Department of Respiratory Disease, West China Hospital, Sichuan University, Chengdu 610041,China.