Flexible large-area ultrasound arrays for medical applications made using embossed polymer structures.

Journal: Nature communications
Published Date:

Abstract

With the huge progress in micro-electronics and artificial intelligence, the ultrasound probe has become the bottleneck in further adoption of ultrasound beyond the clinical setting (e.g. home and monitoring applications). Today, ultrasound transducers have a small aperture, are bulky, contain lead and are expensive to fabricate. Furthermore, they are rigid, which limits their integration into flexible skin patches. New ways to fabricate flexible ultrasound patches have therefore attracted much attention recently. First prototypes typically use the same lead-containing piezo-electric materials, and are made using micro-assembly of rigid active components on plastic or rubber-like substrates. We present an ultrasound transducer-on-foil technology based on thermal embossing of a piezoelectric polymer. High-quality two-dimensional ultrasound images of a tissue mimicking phantom are obtained. Mechanical flexibility and effective area scalability of the transducer are demonstrated by functional integration into an endoscope probe with a small radius of 3 mm and a large area (91.2×14 mm) non-invasive blood pressure sensor.

Authors

  • Paul L M J van Neer
    Acoustics & Underwater Warfare, TNO, The Hague, The Netherlands.
  • Laurens C J M Peters
    Holst Centre, TNO, High Tech Campus 31, 5656 AE, Eindhoven, The Netherlands.
  • Roy G F A Verbeek
    Holst Centre, TNO, High Tech Campus 31, 5656 AE, Eindhoven, The Netherlands.
  • Bart Peeters
    Holst Centre, TNO, High Tech Campus 31, 5656 AE, Eindhoven, The Netherlands.
  • Gerard de Haas
    Holst Centre, TNO, High Tech Campus 31, 5656 AE, Eindhoven, The Netherlands.
  • Lars Hörchens
    Acoustics & Underwater Warfare, TNO, The Hague, The Netherlands.
  • Laurent Fillinger
    Acoustics & Underwater Warfare, TNO, The Hague, The Netherlands.
  • Thijs Schrama
    Acoustics & Underwater Warfare, TNO, The Hague, The Netherlands.
  • Egon J W Merks-Swolfs
    Acoustics & Underwater Warfare, TNO, The Hague, The Netherlands.
  • Kaj Gijsbertse
    Human Performance, TNO, Soesterberg, The Netherlands.
  • Anne E C M Saris
    Medical Ultrasound Imaging Center, Department of Medical Imaging, Radboud university medical centre, Nijmegen, The Netherlands.
  • Moein Mozaffarzadeh
    Medical Ultrasound Imaging Center, Department of Medical Imaging, Radboud university medical centre, Nijmegen, The Netherlands.
  • Jan M Menssen
    Medical Ultrasound Imaging Center, Department of Medical Imaging, Radboud university medical centre, Nijmegen, The Netherlands.
  • Chris L de Korte
    St. Luke's Catholic Hospital and College of Nursing and Midwifery, Wolisso, Ethiopia; Physics of Fluids Group, MIRA, University of Twente, The Netherlands.
  • Jan-Laurens P J van der Steen
    Holst Centre, TNO, High Tech Campus 31, 5656 AE, Eindhoven, The Netherlands.
  • Arno W F Volker
    Acoustics & Underwater Warfare, TNO, The Hague, The Netherlands.
  • Gerwin H Gelinck
    Holst Centre, TNO, High Tech Campus 31, 5656 AE, Eindhoven, The Netherlands. gerwin.gelinck@tno.nl.