Benchmarking machine learning-based real-time respiratory signal predictors in 4D SBRT.

Journal: Medical physics
PMID:

Abstract

BACKGROUND: Stereotactic body radiotherapy of thoracic and abdominal tumors has to account for respiratory intrafractional tumor motion. Commonly, an external breathing signal is continuously acquired that serves as a surrogate of the tumor motion and forms the basis of strategies like breathing-guided imaging and gated dose delivery. However, due to inherent system latencies, there exists a temporal lag between the acquired respiratory signal and the system response. Respiratory signal prediction models aim to compensate for the time delays and to improve imaging and dose delivery.

Authors

  • Lukas Wimmert
    Institute for Applied Medical Informatics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Maximilian Nielsen
    Department of Computational Neuroscience (M.N., T.S., R.W.), University Medical Center-Hamburg-Eppendorf, Germany.
  • Frederic Madesta
  • Tobias Gauer
    Department of Radiotherapy and Radio-Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, 20246, Germany.
  • Christian Hofmann
  • Rene Werner