Significance of the cribriform morphology area ratio for biochemical recurrence in Gleason score 4 + 4 prostate cancer patients following robot-assisted radical prostatectomy.

Journal: Cancer medicine
Published Date: Mar 1, 2024

Abstract

BACKGROUND: In prostate cancer, histological cribriform patterns are categorized as Gleason pattern 4, and recent studies have indicated that their size and percentage are associated with the risk of biochemical recurrence (BCR). However, these studies included a mixture of cases with various Gleason scores (GSs). We therefore examined the prognostic value of the area and percentage of cribriform patterns in patients with GS 4 + 4 prostate cancer.

Authors

  • Kenji Shimodaira
    Department of Urology, Tokyo Medical University, Tokyo, Japan.
  • Rie Inoue
    Anatomic Pathology, Tokyo Medical University, Tokyo, Japan.
  • Takeshi Hashimoto
    Department of Urology, Tokyo Medical University, Tokyo, Japan.
  • Naoya Satake
    Department of Urology, Tokyo Medical University, Tokyo, Japan.
  • Toshihide Shishido
    Department of Urology, Hachioji Medical Center, Tokyo Medical University, 1163, Tatemachi, Hachioji, Tokyo, Japan.
  • Kazunori Namiki
  • Kazuharu Harada
    Department of Health Data Science, Tokyo Medical University, Tokyo, Japan.
  • Toshitaka Nagao
    Department of Anatomic Pathology, Tokyo Medical University, 6-7-1 Nishi Shinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.
  • Yoshio Ohno

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