Development and external validation of a machine learning model for prediction of survival in extremity leiomyosarcoma.

Journal: Surgical oncology
Published Date: Mar 7, 2024

Abstract

PURPOSE: Machine learning (ML) models have been used to predict cancer survival in several sarcoma subtypes. However, none have investigated extremity leiomyosarcoma (LMS). ML is a powerful tool that has the potential to better prognosticate extremity LMS.

Authors

  • Austin Yu
    Department of Orthopedic Surgery, Section of Orthopedic Oncology, Rush University Medical Center, Chicago, IL, USA. Electronic address: austinyu98@gmail.com.
  • Linus Lee
    Department of Orthopedic Surgery, Section of Orthopedic Oncology, Rush University Medical Center, Chicago, IL, USA. Electronic address: linus.h.lee@gmail.com.
  • Thomas Yi
    Warren Alpert Medical School at Brown University, Providence, RI, USA.
  • Michael Fice
    Department of Orthopedic Surgery, Section of Orthopedic Oncology, Rush University Medical Center, Chicago, IL, USA. Electronic address: michael_p_fice@rush.edu.
  • Rohan K Achar
    Department of Orthopedic Surgery, Section of Orthopedic Oncology, Rush University Medical Center, Chicago, IL, USA. Electronic address: ra44139@gmail.com.
  • Sarah Tepper
    Department of Orthopedic Surgery, Section of Orthopedic Oncology, Rush University Medical Center, Chicago, IL, USA. Electronic address: sarah_c_tepper@rush.edu.
  • Conor Jones
    Department of Orthopedic Surgery, Section of Orthopedic Oncology, Rush University Medical Center, Chicago, IL, USA. Electronic address: conor_m_jones@rush.edu.
  • Evan Klein
    Department of Orthopedic Surgery, Section of Orthopedic Oncology, Rush University Medical Center, Chicago, IL, USA. Electronic address: evan_d_klein@rush.edu.
  • Neil Buac
    Department of Orthopedic Surgery, Section of Orthopedic Oncology, Rush University Medical Center, Chicago, IL, USA. Electronic address: neilpatrick_l_buac@rush.edu.
  • Nicolas Lopez-Hisijos
    Department of Pathology, Rush University Medical Center, Chicago, IL, USA. Electronic address: nicolas_lopez-hisijos@rush.edu.
  • Matthew W Colman
    Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison Street, Chicago, IL, 60642, USA.
  • Steven Gitelis
    Department of Orthopedic Surgery, Section of Orthopedic Oncology, Rush University Medical Center, Chicago, IL, USA. Electronic address: steven_gitelis@rush.edu.
  • Alan T Blank
    Department of Orthopedic Surgery, Section of Orthopedic Oncology, Rush University Medical Center, Chicago, IL, USA. Electronic address: alan_blank@rush.edu.

Keywords

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