BACKGROUND AND PURPOSE: Tobacco smoking was prognostic in B-cell lymphomas in the pre-rituximab era, but the association with modern treatment, stage, subtypes, and survival outcomes remains unclear. Patient/material and methods: All patients with di...
Journal of cancer research and clinical oncology
Dec 16, 2025
BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is a major type of kidney cancer, making up about 80% of cases, with advanced stages showing low survival rates. Current treatments face challenges like toxicity and drug resistance. Studies indicat...
BACKGROUND: Machine learning has emerged as a promising tool for survival prediction in various diseases; however, its application and external validation in real-world gastric cancer populations remain limited.
OBJECTIVES: This study aimed to investigate the impact of primary tumor resection (PTR) on survival outcomes for patients with metastatic non-small cell neuroendocrine tumors (mNSCLC-NETs), develop a predictive model to identify which patients may be...
BACKGROUND: We aimed to create a Machine learning (ML) model using patient demographic, clinical and pathological data for prediction of overall survival in patients treated with radical cystectomy (RC). Secondly, we evaluated whether inflammatory ma...
Computer assisted surgery (Abingdon, England)
Sep 8, 2025
To develop a DeepSurv model for predicting survival in pancreatic adenocarcinoma patients, evaluating the benefit of surgical versus non-surgical treatment across different stages, including stage IV subcategories. Clinical data were extracted from t...
BACKGROUND: Skin cutaneous melanoma (SKCM) is the third most common type of cutaneous malignant tumor with a poor prognosis. This research aimed to recognize molecular clusters and develop a novel prognostic signature based on natural killer (NK) cel...
Cervical cancer (CC) is a major cause of mortality in women, with stagnant survival rates, highlighting the need for improved prognostic models. This study aims to develop and compare machine learning models for predicting five-year cause-specific su...
Signal transduction and targeted therapy
May 27, 2025
Early screening, diagnosis, and treatment of lung cancer are pivotal in clinical practice since the tumor stage remains the most dominant factor that affects patient survival. Previous initiatives have tried to develop new tools for decision-making o...
BACKGROUND: Sarcopenia is a clinicopathological condition characterized by a decrease in muscle strength and muscle mass, playing a crucial role in the prognosis of cancer. Therefore, this study aims to investigate the association between sarcopenia ...
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