Explainable Machine Learning Model to Preoperatively Predict Postoperative Complications in Inpatients With Cancer Undergoing Major Operations.

Journal: JCO clinical cancer informatics
PMID:

Abstract

PURPOSE: Preoperative prediction of postoperative complications (PCs) in inpatients with cancer is challenging. We developed an explainable machine learning (ML) model to predict PCs in a heterogenous population of inpatients with cancer undergoing same-hospitalization major operations.

Authors

  • Matthew C Hernandez
    Department of Surgery, University of New Mexico, Albuquerque, NM.
  • Chen Chen
    The George Institute for Global Health, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.
  • Andrew Nguyen
    2Department of Neurosurgery, UC San Diego School of Medicine, San Diego.
  • Kevin Choong
    Department of Surgery, Division of Oncology, Primas Health, University of South Carolina Medical School, Greeneville, SC.
  • Cameron Carlin
    The Laura P. and Leland K. Whittier Virtual Pediatric Intensive Care Unit, Children's Hospital Los Angeles, 4650 Sunset Blvd, Los Angeles, CA 90027, United States. Electronic address: cameronscarlin@gmail.com.
  • Rebecca A Nelson
    Department of Computational and Quantitative Medicine, Division of Biostatistics, City of Hope National Medical Center, Duarte, CA.
  • Lorenzo A Rossi
    Applied AI and Data Science Department, City of Hope National Medical Center, Duarte, California, USA.
  • Naini Seth
    Department of Clinical Informatics, City of Hope National Medical Center, Duarte, CA.
  • Kathy McNeese
    Department of Surgery, University of New Mexico, Albuquerque, NM.
  • Bertram Yuh
    City of Hope National Medical Center, Duarte, California.
  • Zahra Eftekhari
    City of Hope National Medical Center, Duarte, California.
  • Lily L Lai
    Department of Surgery, University of New Mexico, Albuquerque, NM.