Lymph node metastasis prediction and biological pathway associations underlying DCE-MRI deep learning radiomics in invasive breast cancer.

Journal: BMC medical imaging
PMID:

Abstract

BACKGROUND: The relationship between the biological pathways related to deep learning radiomics (DLR) and lymph node metastasis (LNM) of breast cancer is still poorly understood. This study explored the value of DLR based on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in LNM of invasive breast cancer. It also analyzed the biological significance of DLR phenotype based on genomics.

Authors

  • Wenci Liu
    Radiology Imaging Center, The Affiliated Hospital of Guangdong Medical University, 524001, Zhanjiang, Guangdong Province, P. R. China.
  • Wubiao Chen
    Radiology Imaging Center, The Affiliated Hospital of Guangdong Medical University, 524001, Zhanjiang, Guangdong Province, P. R. China.
  • Jun Xia
    Department of Radiology, The First Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen Second People's Hospital, Shenzhen, China. xiajun2003sz@aliyun.com.
  • Zhendong Lu
    Radiology Imaging Center, The Affiliated Hospital of Guangdong Medical University, 524001, Zhanjiang, Guangdong Province, P. R. China.
  • Youwen Fu
    Radiology Imaging Center, The Affiliated Hospital of Guangdong Medical University, 524001, Zhanjiang, Guangdong Province, P. R. China.
  • Yuange Li
    Radiology Imaging Center, The Affiliated Hospital of Guangdong Medical University, 524001, Zhanjiang, Guangdong Province, P. R. China.
  • Zhi Tan
    Graduate School, Woosuk University, Jeonju 514500, Republic of Korea.