Exploring Cognitive Dysfunction in Long COVID Patients: Eye Movement Abnormalities and Frontal-Subcortical Circuits Implications via Eye-Tracking and Machine Learning.

Journal: The American journal of medicine
PMID:

Abstract

BACKGROUND: Cognitive dysfunction is regarded as one of the most severe aftereffects following coronavirus disease 2019 (COVID-19). Eye movements, controlled by several brain areas, such as the dorsolateral prefrontal cortex and frontal-thalamic circuits, provide a potential metric for assessing cortical networks and cognitive status. We aimed to examine the utility of eye movement measurements in identifying cognitive impairments in long COVID patients.

Authors

  • Julián Benito-León
    Department of Neurology, University Hospital "12 de Octubre", Madrid, Spain.
  • José Lapeña
    Department of Neurology, University Hospital "12 de Octubre", Madrid, Spain.
  • Lorena García-Vasco
    Department of Neurology, University Hospital "12 de Octubre", Madrid, Spain.
  • Constanza Cuevas
    Department of Neurology, University Hospital "12 de Octubre", Madrid, Spain.
  • Julie Viloria-Porto
    Magdalena University, Santa Marta, Colombia; ETSIDI-Center for Automation and Robotics UPM-CSIC, Universidad Politécnica de Madrid, Madrid, Spain.
  • Alberto Calvo-Córdoba
    ETSIDI-Center for Automation and Robotics UPM-CSIC, Universidad Politécnica de Madrid, Madrid, Spain.
  • Estíbaliz Arrieta-Ortubay
    Department of Internal Medicine, University Hospital "12 de Octubre", Madrid, Spain.
  • María Ruiz-Ruigómez
    Department of Internal Medicine, University Hospital "12 de Octubre", Madrid, Spain.
  • Carmen Sánchez-Sánchez
    Department of Neurology, University Hospital "12 de Octubre", Madrid, Spain.
  • Cecilia García-Cena
    ETSIDI-Center for Automation and Robotics UPM-CSIC, Universidad Politécnica de Madrid, Madrid, Spain.