Pharmacokinetic evaluation of intrapleural perfusion with hyperthermic chemotherapy using cisplatin in patients with malignant pleural effusion.

Journal: Lung cancer (Amsterdam, Netherlands)
PMID: 28213004

Abstract

OBJECTIVES: Malignant pleural effusion (MPE) has a poor prognosis. Most patients are treated with tube thoracostomy and sclerotherapy, although its success rate is around 64%. We have investigated intrapleural perfusion with hyperthermic chemotherapy (IPHC) using cisplatin in a study with a pharmacokinetic evaluation.

Authors

  • Hirozo Sakaguchi
    Department of General Thoracic Surgery, Saitama Medical University International Medical Center, Saitama, Japan.
  • H Ishida
    Department of General Thoracic Surgery, Saitama Medical University International Medical Center, Saitama, Japan.
  • H Nitanda
    Department of General Thoracic Surgery, Saitama Medical University International Medical Center, Saitama, Japan.
  • N Yamazaki
    Department of General Thoracic Surgery, Saitama Medical University International Medical Center, Saitama, Japan.
  • K Kaneko
    Department of General Thoracic Surgery, Saitama Medical University International Medical Center, Saitama, Japan.
  • Kunihiko Kobayashi
    Department of General Thoracic Surgery, Saitama Medical University International Medical Center, Saitama, Japan. Electronic address: kobakuni@saitama-med.ac.jp.

Keywords

External Resources

Popular Topics
Recent Journals