Gan to kagaku ryoho. Cancer & chemotherapy
38303206
INTRODUCTION: The key drugs of first-line chemotherapy for metastatic esophageal cancer are 5-FU and cisplatin(CF). However, the treatment strategy for unfit patients of CF regimen remains controversial.
Deep learning-enabled smartphone-based image processing has significant advantages in the development of point-of-care diagnostics. Conventionally, most deep-learning applications require task specific large scale expertly annotated datasets. Therefo...
Platinum-based chemotherapy is the cornerstone treatment for female high-grade serous ovarian carcinoma (HGSOC), but choosing an appropriate treatment for patients hinges on their responsiveness to it. Currently, no available biomarkers can promptly ...
As hazardous waste, the massive generation of spent auto-exhaust catalysts (SACs) puts enormous pressure on environmental management, but provides a rare opportunity for platinum group metals (PGMs) recycling. In this study, machine learning (ML) met...
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
39083703
PURPOSE: Cancers with homologous recombination deficiency (HRD) can benefit from platinum salts and poly(ADP-ribose) polymerase inhibitors. Standard diagnostic tests for detecting HRD require molecular profiling, which is not universally available.
On the international level, it is common to act on reducing emissions from energy systems. However, in addition to industrial emissions, low-stack emissions also make a significant contribution. A good step in reducing its environmental impact, is to...
Conventional methods for detecting unsaturated fatty acids (UFAs) pose challenges for rapid analyses due to the need for complex pretreatment and expensive instruments. Here, we developed an intelligent platform for facile and low-cost analysis of UF...
Bacterial biofilms are complex multicellular communities that adhere firmly to solid surfaces. They are widely recognized as major threats to human health, contributing to issues such as persistent infections on medical implants and severe contaminat...
Gold nanoparticles (GNPs), which appear red, are widely used as labels in lateral flow assays (LFAs) for visual detection. However, in blood-derived samples, hemolysis─caused by the rupture of red blood cells and the release of hemoglobin─creates a r...
BACKGROUND: The study aimed at developing and validating a deep learning (DL) model based on the ultrasound imaging for predicting the platinum resistance of patients with epithelial ovarian cancer (EOC).