AIMC Topic: Platinum

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Split DNA Tetrahedron-Mediated Spatiotemporal-Hierarchy CRISPR Cascade Integrated with Au@Pt Nanolabels and Artificial Intelligence for a Cervical Cancer MicroRNA Bioassay.

ACS nano
The screening and monitoring of microRNAs as cancer molecular biomarkers is clinically significant, but traditional methods lack sufficient sensitivity, accuracy, and convenience. The CRISPR-colorimetric lateral flow assay (CLFA) integration offers a...

Addressing Hemolysis-Induced Loss of Sensitivity in Lateral Flow Assays of Blood Samples with Platinum-Coated Gold Nanoparticles and Machine Learning.

Analytical chemistry
Gold nanoparticles (GNPs), which appear red, are widely used as labels in lateral flow assays (LFAs) for visual detection. However, in blood-derived samples, hemolysis─caused by the rupture of red blood cells and the release of hemoglobin─creates a r...

Active Microrobots for Dual Removal of Biofilms via Chemical and Physical Mechanisms.

ACS applied materials & interfaces
Bacterial biofilms are complex multicellular communities that adhere firmly to solid surfaces. They are widely recognized as major threats to human health, contributing to issues such as persistent infections on medical implants and severe contaminat...

Smartphone-Assisted Nanozyme Colorimetric Sensor Array Combined "Image Segmentation-Feature Extraction" Deep Learning for Detecting Unsaturated Fatty Acids.

ACS sensors
Conventional methods for detecting unsaturated fatty acids (UFAs) pose challenges for rapid analyses due to the need for complex pretreatment and expensive instruments. Here, we developed an intelligent platform for facile and low-cost analysis of UF...

Deep Learning Artificial Intelligence Predicts Homologous Recombination Deficiency and Platinum Response From Histologic Slides.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology
PURPOSE: Cancers with homologous recombination deficiency (HRD) can benefit from platinum salts and poly(ADP-ribose) polymerase inhibitors. Standard diagnostic tests for detecting HRD require molecular profiling, which is not universally available.

Application of triple-branch artificial neural network system for catalytic pellets combustion.

Journal of environmental management
On the international level, it is common to act on reducing emissions from energy systems. However, in addition to industrial emissions, low-stack emissions also make a significant contribution. A good step in reducing its environmental impact, is to...

Potential prediction and coupling relationship revealing for recovery of platinum group metals from spent auto-exhaust catalysts based on machine learning.

Journal of environmental management
As hazardous waste, the massive generation of spent auto-exhaust catalysts (SACs) puts enormous pressure on environmental management, but provides a rare opportunity for platinum group metals (PGMs) recycling. In this study, machine learning (ML) met...

Histopathologic image-based deep learning classifier for predicting platinum-based treatment responses in high-grade serous ovarian cancer.

Nature communications
Platinum-based chemotherapy is the cornerstone treatment for female high-grade serous ovarian carcinoma (HGSOC), but choosing an appropriate treatment for patients hinges on their responsiveness to it. Currently, no available biomarkers can promptly ...

Deep learning-assisted sensitive detection of fentanyl using a bubbling-microchip.

Lab on a chip
Deep learning-enabled smartphone-based image processing has significant advantages in the development of point-of-care diagnostics. Conventionally, most deep-learning applications require task specific large scale expertly annotated datasets. Therefo...

Automated Image Analysis for Single-Atom Detection in Catalytic Materials by Transmission Electron Microscopy.

Journal of the American Chemical Society
Single-atom catalytic sites may have existed in all supported transition metal catalysts since their first application. Yet, interest in the design of single-atom heterogeneous catalysts (SACs) only really grew when advances in transmission electron ...