Towards a machine-learning assisted non-invasive classification of dengue severity using wearable PPG data: a prospective clinical study.

Journal: EBioMedicine
PMID: 38815363

Abstract

BACKGROUND: Dengue epidemics impose considerable strain on healthcare resources. Real-time continuous and non-invasive monitoring of patients admitted to the hospital could lead to improved care and outcomes. We evaluated the performance of a commercially available wearable (SmartCare) utilising photoplethysmography (PPG) to stratify clinical risk for a cohort of hospitalised patients with dengue in Vietnam.

Authors

  • Stefan Karolcik
    Centre for Bio Inspired Technology, Imperial College London, England.
  • Vasileos Manginas
    Centre for Bio-Inspired Technology, Imperial College London, South Kensington Campus, London, SW7 2AZ, United Kingdom.
  • Ho Quang Chanh
    Oxford University Clinical Research Unit, 764 Vo Van Kiet Street, District 5, Ho Chi Minh City, 72708, Viet Nam.
  • John Daniels
  • Nguyen Thi Giang
    Oxford University Clinical Research Unit (OUCRU), Hospital for Tropical Diseases, Ho Chi Minh City, 700000, Viet Nam.
  • Vu Ngo Thanh Huyen
    Oxford University Clinical Research Unit (OUCRU), Hospital for Tropical Diseases, Ho Chi Minh City, 700000, Viet Nam.
  • Minh Tu Van Hoang
    Oxford University Clinical Research Unit (OUCRU), Hospital for Tropical Diseases, Ho Chi Minh City, 700000, Viet Nam.
  • Khanh Phan Nguyen Quoc
    Oxford University Clinical Research Unit (OUCRU), Hospital for Tropical Diseases, Ho Chi Minh City, 700000, Viet Nam.
  • Bernard Hernandez
    Centre for Bio-Inspired Technology, Department of Electrical and Electronic Engineering, Imperial College London, B422 Bessemer Building, South Kensington Campus, London, SW7 2AZ, UK. b.hernandez-perez@imperial.ac.uk.
  • Damien K Ming
    Centre for Antimicrobial Optimisation, Imperial College London, England.
  • Hao Nguyen Van
    Oxford University Clinical Research Unit (OUCRU), Hospital for Tropical Diseases, Ho Chi Minh City, 700000, Viet Nam.
  • Tu Qui Phan
    Oxford University Clinical Research Unit (OUCRU), Hospital for Tropical Diseases, Ho Chi Minh City, 700000, Viet Nam.
  • Huynh Trung Trieu
    Hospital for Tropical Diseases, Ho Chi Minh City, Viet Nam.
  • Tai Luong Thi Hue
    Oxford University Clinical Research Unit (OUCRU), Hospital for Tropical Diseases, Ho Chi Minh City, 700000, Viet Nam.
  • Alison H Holmes
    Health Protection Unit in Healthcare Associated infections and Antimicrobial Resistance, Imperial College London, 8th floor Commonwealth Building, Hammersmith Hospital Campus, Acton, London, W12 0NN, UK.
  • Louise Thwaites
    Oxford University Clinical Research Unit, Ho Chi Minh City and Hanoi, Vietnam.
  • Tho Phan Vinh
    Oxford University Clinical Research Unit (OUCRU), Hospital for Tropical Diseases, Ho Chi Minh City, 700000, Viet Nam.
  • Sophie Yacoub
    Oxford University Clinical Research Unit, Ho Chi Minh City and Hanoi, Vietnam.
  • Pantelis Georgiou

Keywords

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