Labelling with dynamics: A data-efficient learning paradigm for medical image segmentation.

Journal: Medical image analysis
Published Date:

Abstract

The success of deep learning on image classification and recognition tasks has led to new applications in diverse contexts, including the field of medical imaging. However, two properties of deep neural networks (DNNs) may limit their future use in medical applications. The first is that DNNs require a large amount of labeled training data, and the second is that the deep learning-based models lack interpretability. In this paper, we propose and investigate a data-efficient framework for the task of general medical image segmentation. We address the two aforementioned challenges by introducing domain knowledge in the form of a strong prior into a deep learning framework. This prior is expressed by a customized dynamical system. We performed experiments on two different datasets, namely JSRT and ISIC2016 (heart and lungs segmentation on chest X-ray images and skin lesion segmentation on dermoscopy images). We have achieved competitive results using the same amount of training data compared to the state-of-the-art methods. More importantly, we demonstrate that our framework is extremely data-efficient, and it can achieve reliable results using extremely limited training data. Furthermore, the proposed method is rotationally invariant and insensitive to initialization.

Authors

  • Yuanhan Mo
    School of Computer Science, National Centre for Text Mining, The University of Manchester, Manchester, UK. maxmo2009@gmail.com.
  • Fangde Liu
  • Guang Yang
    National Heart and Lung Institute, Imperial College London, London, UK.
  • Shuo Wang
    College of Tea & Food Science, Anhui Agricultural University, Hefei, China.
  • Jianqing Zheng
    The Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
  • Fuping Wu
    School of Data Science, Fudan University, Shanghai, China; Dept of Statistics, School of Management, Fudan University, Shanghai, China.
  • BartÅ‚omiej W Papież
    Big Data Institute, University of Oxford, UK.
  • Douglas McIlwraith
    Data Science Institute, Imperial College London, UK.
  • Taigang He
    St George's, University of London, UK.
  • Yike Guo
    Department of Computing, Imperial College, London SW7 2AZ, UK. y.guo@imperial.ac.uk.