A ResNet mini architecture for brain age prediction.

Journal: Scientific reports
Published Date:

Abstract

The brain presents age-related structural and functional changes in the human life, with different extends between subjects and groups. Brain age prediction can be used to evaluate the development and aging of human brain, as well as providing valuable information for neurodevelopment and disease diagnosis. Many contributions have been made for this purpose, resorting to different machine learning methods. To solve this task and reduce memory resource consumption, we develop a mini architecture of only 10 layers by modifying the deep residual neural network (ResNet), named ResNet mini architecture. To support the ResNet mini architecture in brain age prediction, the brain age dataset (OpenNeuro #ds000228) that consists of 155 study participants (three classes) and the Alzheimer MRI preprocessed dataset that consists of 6400 images (four classes) are employed. We compared the performance of the ResNet mini architecture with other popular networks using the two considered datasets. Experimental results show that the proposed architecture exhibits generality and robustness with high accuracy and less parameter number.

Authors

  • Xuan Zhang
  • Si-Yuan Duan
    College of Computer Science, Sichuan University, Chengdu, 610065, China.
  • Si-Qi Wang
    College of Engineering, Shantou University, Shantou, 515063, China.
  • Yao-Wen Chen
    College of Engineering, Shantou University, Shantou, 515063, China.
  • Shi-Xin Lai
    College of Engineering, Shantou University, Shantou, 515063, China.
  • Ji-Sheng Zou
    College of Engineering, Shantou University, Shantou, 515063, China.
  • Yan Cheng
    The First Clinical Medical College of Shaanxi University of Chinese Medicine, Xianyang, China.
  • Ji-Tian Guan
    Department of Radiology, Second Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China.
  • Ren-Hua Wu
    Department of Radiology, Second Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China. cjr.wurenhua@vip.163.com.
  • Xiao-Lei Zhang
    Center for Intelligent Acoustics and Immersive Communications, School of Marine Science and Technology, Northwestern Polytechnical University, China. Electronic address: xiaolei.zhang@nwpu.edu.cn.