Radiomics and artificial intelligence applications in pediatric brain tumors.

Journal: World journal of pediatrics : WJP
Published Date:

Abstract

BACKGROUND: The study of central nervous system (CNS) tumors is particularly relevant in the pediatric population because of their relatively high frequency in this demographic and the significant impact on disease- and treatment-related morbidity and mortality. While both morphological and non-morphological magnetic resonance imaging techniques can give important information concerning tumor characterization, grading, and patient prognosis, increasing evidence in recent years has highlighted the need for personalized treatment and the development of quantitative imaging parameters that can predict the nature of the lesion and its possible evolution. For this purpose, radiomics and the use of artificial intelligence software, aimed at obtaining valuable data from images beyond mere visual observation, are gaining increasing importance. This brief review illustrates the current state of the art of this new imaging approach and its contributions to understanding CNS tumors in children.

Authors

  • Francesco Pacchiano
    Department of Precision Medicine, University of Campania "L. Vanvitelli", Caserta, Italy.
  • Mario Tortora
    Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
  • Chiara Doneda
    Department of Pediatric Radiology and Neuroradiology, V. Buzzi Children's Hospital, Milan, Italy.
  • Giana Izzo
    Department of Pediatric Radiology and Neuroradiology, V. Buzzi Children's Hospital, Milan, Italy.
  • Filippo Arrigoni
    Neuroimaging Unit, Scientific Institute IRCCS "Eugenio Medea", Bosisio Parini (Lecco), Italy.
  • Lorenzo Ugga
    Department of Advanced Biomedical Sciences, University of Naples "Federico II", Via S. Pansini, 5, 80131, Naples, Italy.
  • Renato Cuocolo
    Department of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, Italy.
  • Cecilia Parazzini
    Department of Pediatric Radiology and Neuroradiology,Children Hospital "V. Buzzi", Milan, Italy.
  • Andrea Righini
    Department of Pediatric Radiology and Neuroradiology,Children Hospital "V. Buzzi", Milan, Italy.
  • Arturo Brunetti
    Department of Advanced Biomedical Sciences, University of Naples "Federico II,", Naples, Italy.