LDSG-Net: an efficient lightweight convolutional neural network for acute hypotensive episode prediction during ICU hospitalization.

Journal: Physiological measurement
PMID:

Abstract

. Acute hypotension episode (AHE) is one of the most critical complications in intensive care unit (ICU). A timely and precise AHE prediction system can provide clinicians with sufficient time to respond with proper therapeutic measures, playing a crucial role in saving patients' lives. Recent studies have focused on utilizing more complex models to improve predictive performance. However, these models are not suitable for clinical application due to limited computing resources for bedside monitors.. To address this challenge, we propose an efficient lightweight dilated shuffle group network. It effectively incorporates shuffling operations into grouped convolutions on the channel and dilated convolutions on the temporal dimension, enhancing global and local feature extraction while reducing computational load.. Our benchmarking experiments on the MIMIC-III and VitalDB datasets, comprising 6036 samples from 1304 patients and 2958 samples from 1047 patients, respectively, demonstrate that our model outperforms other state-of-the-art lightweight CNNs in terms of balancing parameters and computational complexity. Additionally, we discovered that the utilization of multiple physiological signals significantly improves the performance of AHE prediction. External validation on the MIMIC-IV dataset confirmed our findings, with prediction accuracy for AHE 5 min prior reaching 93.04% and 92.04% on the MIMIC-III and VitalDB datasets, respectively, and 89.47% in external verification.. Our study demonstrates the potential of lightweight CNN architectures in clinical applications, providing a promising solution for real-time AHE prediction under resource constraints in ICU settings, thereby marking a significant step forward in improving patient care.

Authors

  • Longfei Liu
    Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, People's Republic of China.
  • Yujie Hang
    Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, People's Republic of China.
  • Rongqin Chen
    College of Biosystems Engineering and Food Science, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China.
  • Xianliang He
    Shenzhen Mindray Bio-Medical Electronics Co., Ltd, Shenzhen, Guangdong, People's Republic of China.
  • Xingliang Jin
    Shenzhen Mindray Bio-Medical Electronics Co., Ltd, Shenzhen, Guangdong, People's Republic of China.
  • Dan Wu
    Xi'an Aerospace Propulsion Institute, Xi'an 710049, China.
  • Ye Li
    Environment and Plant Protection Institute, Chinese Academy of Tropical Agricultural Science, Haikou 571010, People's Republic of China; Key Laboratory of Monitoring and Control of Tropical Agricultural and Forest Invasive Alien Pests, Ministry of Agriculture, Haikou 571010, People's Republic of China.