Development and external validation of a dynamic risk score for early prediction of cardiogenic shock in cardiac intensive care units using machine learning.

Journal: European heart journal. Acute cardiovascular care
PMID:

Abstract

AIMS: Myocardial infarction and heart failure are major cardiovascular diseases that affect millions of people in the USA with morbidity and mortality being highest among patients who develop cardiogenic shock. Early recognition of cardiogenic shock allows prompt implementation of treatment measures. Our objective is to develop a new dynamic risk score, called CShock, to improve early detection of cardiogenic shock in the cardiac intensive care unit (ICU).

Authors

  • Yuxuan Hu
    Leon H. Charney Division of Cardiology, NYU Langone Health, New York, NY, USA.
  • Albert Lui
    NYU Grossman School of Medicine, New York, USA.
  • Mark Goldstein
    Courant Institute of Mathematical Sciences, New York University, New York, New York, USA.
  • Mukund Sudarshan
    Courant Institute of Mathematical Sciences, New York University.
  • Andrea Tinsay
    Department of Medicine, NYU Langone Health, New York, USA.
  • Cindy Tsui
    Department of Medicine, NYU Langone Health, New York, USA.
  • Samuel D Maidman
    Department of Medicine, NYU Langone Health, New York, USA.
  • John Medamana
    Department of Medicine, NYU Langone Health, New York, USA.
  • Neil Jethani
    Department of Population Health, NYU Langone Health, New York University School of Medicine, New York, New York, USA; Courant Institute of Mathematical Sciences, New York University, New York, New York, USA.
  • Aahlad Puli
    Department of Computer Science, New York University.
  • Vuthy Nguy
    Department of Population Health, NYU Langone Health, New York, USA.
  • Yindalon Aphinyanaphongs
    Department of Population Health, New York University, New York.
  • Nicholas Kiefer
    Leon. H. Charney Division of Cardiology, NYU Langone Health, 550 1st Avenue, New York, NY 10016, USA.
  • Nathaniel R Smilowitz
    Leon. H. Charney Division of Cardiology, NYU Langone Health, 550 1st Avenue, New York, NY 10016, USA.
  • James Horowitz
    Leon. H. Charney Division of Cardiology, NYU Langone Health, 550 1st Avenue, New York, NY 10016, USA.
  • Tania Ahuja
    Department of Pharmacy, NYU Langone Health, New York, USA.
  • Glenn I Fishman
    Leon. H. Charney Division of Cardiology, NYU Langone Health, 550 1st Avenue, New York, NY 10016, USA.
  • Judith Hochman
    Leon. H. Charney Division of Cardiology, NYU Langone Health, 550 1st Avenue, New York, NY 10016, USA.
  • Stuart Katz
    Leon. H. Charney Division of Cardiology, NYU Langone Health, 550 1st Avenue, New York, NY 10016, USA.
  • Samuel Bernard
    Leon. H. Charney Division of Cardiology, NYU Langone Health, 550 1st Avenue, New York, NY 10016, USA.
  • Rajesh Ranganath
    Department of Computer Science, New York University.