A Three-Stage Semi-Supervised Learning Approach to Spine Image Segmentation.

Journal: Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
PMID:

Abstract

Spine segmentation in computed tomography (CT) images is critical for automatic analysis, especially when focusing on varied spinal anatomy. Despite having comprehensive annotations for normal vertebrae, many datasets do not encompass labeled fracture data, posing challenges for predictive modeling. This research presents a three-stage 2.5D semi-supervised learning based on U-Net that utilizes both labeled and unlabeled datasets. The objectives are to reduce workload needed for manual annotation and create a model proficient in processing fracture data without prior specific fracture dataset with labeling. Due to the similarity between the vertebrae, precise segmentation is difficult. We utilized a cascade framework, which is aligned to a structured clinical examination process of the vertebral segments in order to achieve more precise delineation. In view of the voluminous data in 3D CT images and GPU performance constraints, this study strategically employs 2D network training, further supplemented by 2.5D network input, to optimize model performance. Preliminary findings suggest that this approach significantly improves the model's ability to segment spine regions, especially in environments with limited equipment capabilities. Further evaluation is required to understand its full potential in various scenarios, including impact on detection of fractures.

Authors

  • Ruixiang Pan
  • Xiaohong Wang
    School of Reliability and Systems Engineering, Beihang University, Beijing 100191, China. wxhong@buaa.edu.cn.
  • Zhiping Lin
    School of Electrical and Electronic Engineering, Nanyang Technological University, Nanyang Avenue, 639798, Singapore. Electronic address: ezplin@ntu.edu.sg.
  • Chi Longn Ho
  • Oliver James Nickalls
  • Cynthia Assimta Peter
  • Donovan Tay
  • Weimin Huang