BACKGROUND: A severe form of pathological social withdrawal, 'hikikomori,' has been acknowledged in Japan, spreading worldwide, and becoming a global health issue. The pathophysiology of hikikomori has not been clarified, and its biological traits re...
Digital technology, including its omnipresent connectedness and its powerful artificial intelligence, is the most recent long wave of humanity's socioeconomic evolution. The first technological revolutions go all the way back to the Stone, Bronze, an...