AIMC Topic: Uric Acid

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Construction and validation of a urinary stone composition prediction model based on machine learning.

Urolithiasis
The composition of urinary calculi serves as a critical determinant for personalized surgical strategies; however, such compositional data are often unavailable preoperatively. This study aims to develop a machine learning-based preoperative predicti...

Multi-component metabolite electrochemical detection and analysis based on machine learning.

Analytical methods : advancing methods and applications
Metabolic molecules are highly correlated with various physiological indicators and diseases, so it is particularly important to monitor the levels of multiple metabolites in the body. Due to the similar electrochemical properties of uric acid (UA), ...

Interpretive prediction of hyperuricemia and gout patients via machine learning analysis of human gut microbiome.

BMC microbiology
Hyperuricemia (HUA) and gout result from imbalances in uric acid metabolism and are closely associated with the gut microbiota. Advanced analytical methods facilitate the exploration of microbiota complexity. In this study, 16S rRNA sequencing data f...

Physiological serum uric acid concentrations correlate with arterial stiffness in a sex-dependent manner.

BMC medicine
BACKGROUND: In humans, uric acid is a product of purine metabolism that impacts the vascular system. In addition to effects on arterial vascular tone, associations between serum uric acid concentrations-even in the physiological range-and arterial hy...

A supervised machine learning approach with feature selection for sex-specific biomarker prediction.

NPJ systems biology and applications
Biomarkers are crucial in aiding in disease diagnosis, prognosis, and treatment selection. Machine learning (ML) has emerged as an effective tool for identifying novel biomarkers and enhancing predictive modelling. However, sex-based bias in ML algor...

Multimodal Wearable Sensing for Biomechanics and Biomolecules Enabled by the M-MPM/VCFs@Ag Interface with Machine Learning Pipeline.

ACS sensors
The addition sensing device of sweat to wearable biostress sensors would eliminate the need for using multiple gadgets for healthcare analysis. Due to the distinct package fashion of sensor interface for biostress and biomolecule, achieving permeabil...

Maternal and umbilical cord plasma purine concentrations after oral carbohydrate loading prior to elective Cesarean delivery under spinal anesthesia: a randomized controlled trial.

BMC pregnancy and childbirth
OBJECTIVE: To evaluate the effect of preoperative intake of oral carbohydrates versus standard preoperative fasting prior to elective cesarean delivery on plasma purine levels (hypoxanthine, xanthine, and uric acid) and beta-hydroxybutyrate (β-HB) in...

MXene-enabled organic synaptic fiber for ultralow-power and biochemical-mediated neuromorphic transistor.

Biosensors & bioelectronics
Fibrous bioelectronic provides an intrinsically accessible platform for artificial nerve and real-time physiological perception. However, advanced fiber-based artificial synapse remains a challenge due to the contradictory conductance demands for bra...

Tlalpan 2020 Case Study: Enhancing Uric Acid Level Prediction with Machine Learning Regression and Cross-Feature Selection.

Nutrients
Uric acid is a key metabolic byproduct of purine degradation and plays a dual role in human health. At physiological levels, it acts as an antioxidant, protecting against oxidative stress. However, excessive uric acid can lead to hyperuricemia, cont...

Machine learning-based prediction models for renal impairment in Chinese adults with hyperuricaemia: risk factor analysis.

Scientific reports
In hyperuricaemic populations, multiple factors may contribute to impaired renal function. This study aimed to establish a machine learning-based model to identify characteristic factors related to renal impairment in hyperuricaemic patients, determi...