AI Medical Compendium Journal:
Journal of ginseng research

Showing 11 to 20 of 31 articles

A proteomic approach reveals the differential protein expression in treated with red ginseng extract ().

Journal of ginseng research
BACKGROUND: Red ginseng is a popularly used traditional medicine with antiaging effects in Asian countries. The present study aimed to explore the changes in protein expression underlying the mechanisms of life span extension and antiaging caused by ...

Production of bioactive ginsenoside Rg3(S) and compound K using recombinant .

Journal of ginseng research
BACKGROUND: Ginsenoside Rg3(S) and compound K (C-K) are pharmacologically active components of ginseng that promote human health and improve quality of life. The aim of this study was to produce Rg3(S) and C-K from ginseng extract using recombinant .

Gintonin absorption in intestinal model systems.

Journal of ginseng research
BACKGROUND: Recently, we identified a novel ginseng-derived lysophosphatidic acid receptor ligand, called gintonin. We showed that gintonin induces [Ca]i transient-mediated morphological changes, proliferation, and migration in cells expressing lysop...

Evaluation of ginsenoside bioconversion of lactic acid bacteria isolated from kimchi.

Journal of ginseng research
BACKGROUND: is a physiologically active plant widely used in traditional medicine that is characterized by the presence of ginsenosides. Rb1, a major ginsenoside, is used as the starting material for producing ginsenoside derivatives with enhanced p...

Korean Red Ginseng extract induces angiogenesis through activation of glucocorticoid receptor.

Journal of ginseng research
BACKGROUND: Our previous studies have demonstrated that ginsenoside-Rg1 can promote angiogenesis and through activation of the glucocorticoid receptor (GR). Furthermore, microRNA (miRNA) expression profiling has shown that Rg1 can modulate the expr...

Ginseng essence, a medicinal and edible herbal formulation, ameliorates carbon tetrachloride-induced oxidative stress and liver injury in rats.

Journal of ginseng research
BACKGROUND: Ginseng essence (GE) is a formulation comprising four medicinal and edible herbs including ginseng (), American ginseng (), lotus seed (), and lily bulb (). This study was aimed at investigating the hepatoprotective effect of GE against c...

Processed , sun ginseng, inhibits the differentiation and proliferation of 3T3-L1 preadipocytes and fat accumulation in .

Journal of ginseng research
BACKGROUND: Heat-processed ginseng, sun ginseng (SG), has been reported to have improved therapeutic properties compared with raw forms, such as increased antidiabetic, anti-inflammatory, and antihyperglycemic effects. The aim of this study was to in...

Protective effect of ginsenosides Rk3 and Rh4 on cisplatin-induced acute kidney injury and .

Journal of ginseng research
BACKGROUND: Nephrotoxicity is the major side effect in cisplatin chemotherapy. Previously, we reported that the ginsenosides Rk3 and Rh4 reduced cisplatin toxicity on porcine renal proximal epithelial tubular cells (LLC-PK1). Here, we aimed to evalua...

Effect of B-complex vitamins on the antifatigue activity and bioavailability of ginsenoside Re after oral administration.

Journal of ginseng research
BACKGROUND: Both ginsenoside Re and B-complex vitamins are widely used as nutritional supplements. They are often taken together so as to fully utilize their antifatigue and refreshing effects, respectively. Whether actually a drug-nutrient interacti...

Preventive effect of fermented black ginseng against cisplatin-induced nephrotoxicity in rats.

Journal of ginseng research
BACKGROUND: Fermented black ginseng (FBG) is processed ginseng by the repeated heat treatment and fermentation of raw ginseng. The protective effect and mechanism of FBG on cisplatin-induced nephrotoxicity was investigated to evaluate its therapeutic...