AIMC Topic: Chromatography
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Prediction of delayed retention of antibodies in hydrophobic interaction chromatography from sequence using machine learning.
Bioinformatics (Oxford, England)
Dec 1, 2017
MOTIVATION: The hydrophobicity of a monoclonal antibody is an important biophysical property relevant for its developability into a therapeutic. In addition to characterizing heterogeneity, Hydrophobic Interaction Chromatography (HIC) is an assay tha...
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