AIMC Topic: Citrullination

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Deep Learning Enhances Precision of Citrullination Identification in Human and Plant Tissue Proteomes.

Molecular & cellular proteomics : MCP Feb 5, 2025
Citrullination is a critical yet understudied post-translational modification (PTM) implicated in various biological processes. Exploring its role in health and disease requires a comprehensive understanding of the prevalence of this PTM at a proteom...
Humans Deep Learning Proteomics Proteome Protein Processing, Post-Translational Plant Proteins Arabidopsis Citrullination
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Investigating the Precise Identification of Citrullination Sites with High- Performance Score Metrics Using a Powerful Computation Predicting Tool.

Combinatorial chemistry & high throughput screening Jan 1, 2024
BACKGROUND: To elucidate the detailed mechanisms of citrullination at the molecular level and design drugs applicable to major human diseases, predicting protein citrullination sites (PCSs) is essential. Using experimental approaches to predict PCSs ...
Humans Machine Learning Computational Biology Support Vector Machine Citrullination
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Prediction of Citrullination Sites on the Basis of mRMR Method and SNN.

Combinatorial chemistry & high throughput screening Jan 1, 2019
BACKGROUND: Citrullination, an important post-translational modification of proteins, alters the molecular weight and electrostatic charge of the protein side chains. Citrulline, in protein sequences, is catalyzed by a class of Peptidyl Arginine Deim...
Humans Neural Networks, Computer Algorithms Computational Biology Citrullination Citrulline
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