Interdisciplinary sciences, computational life sciences
Jun 17, 2022
Protein subcellular localization prediction is an important research area in bioinformatics, which plays an essential role in understanding protein function and mechanism. Many machine learning and deep learning algorithms have been employed for this...
Analytical chemistry
Jun 16, 2022
The amount of available biological data has exploded since the emergence of high-throughput technologies, which is not only revolting the way we recognize molecules and diseases but also bringing novel analytical challenges to bioinformatics analysis...
International journal of molecular sciences
Jun 14, 2022
In recent years, deep learning has emerged as a highly active research field, achieving great success in various machine learning areas, including image processing, speech recognition, and natural language processing, and now rapidly becoming a domin...
Sensors (Basel, Switzerland)
Jun 11, 2022
Development and operations (DevOps), artificial intelligence (AI), big data and edge-fog-cloud are disruptive technologies that may produce a radical transformation of the industry. Nevertheless, there are still major challenges to efficiently applyi...
Journal of proteome research
Jun 10, 2022
In their recent review ( 2022, 21 (4), 849-864), Crook et al. diligently discuss the basics (and less basics) of Bayesian modeling, survey its various applications to proteomics, and highlight its potential for the improvement of computational prote...
IEEE/ACM transactions on computational biology and bioinformatics
Jun 3, 2022
Among all the PTMs, the protein phosphorylation is pivotal for various pathological and physiological processes. About 30 percent of eukaryotic proteins undergo the phosphorylation modification, leading to various changes in conformation, function, s...
IEEE/ACM transactions on computational biology and bioinformatics
Jun 3, 2022
Long non-coding RNA(lncRNA) can interact with microRNA(miRNA) and play an important role in inhibiting or activating the expression of target genes and the occurrence and development of tumors. Accumulating studies focus on the prediction of miRNA-ln...
IEEE/ACM transactions on computational biology and bioinformatics
Jun 3, 2022
It has been proved that long noncoding RNA (lncRNA) plays critical roles in many human diseases. Therefore, inferring associations between lncRNAs and diseases can contribute to disease diagnosis, prognosis and treatment. To overcome the limitation o...
Computers in biology and medicine
Jun 1, 2022
Locating the promoter region in DNA sequences is of paramount importance in bioinformatics. This problem has been widely studied in the literature, but it has not yet been fully resolved. Some researchers have shown remarkable results using convoluti...
Journal of computational biology : a journal of computational molecular cell biology
May 27, 2022